Name | Diflubenzuron |
Synonyms | Largon Dimilin oms1804 difluron OMS 1804 PH 60-40 pdd6040i Micromite DU 112307 PDD 6040-I Diflubenzuron Diflubenzuron E.C. 1-(4-chlorophenyl)-3-(2,6-difluorobenzoyl)urea 3-(2,6-Difluorobenzoyl)-1-(4-chlorophenyl)urea N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide N-(((4-chlorophenyl)amino)carbonyl)-2,6-difluorobenzamide |
CAS | 35367-38-5 |
EINECS | 252-529-3 |
InChI | InChI=1/C14H9ClF2N2O2.C12H6Cl4O2S/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17;13-7-1-3-8(4-2-7)19(17,18)12-6-10(15)9(14)5-11(12)16/h1-7H,(H2,18,19,20,21);1-6H |
Molecular Formula | C14H9ClF2N2O2 |
Molar Mass | 310.68 |
Density | 1.4301 (estimate) |
Melting Point | 230-232°C |
Water Solubility | 0.008 g/100 mL |
Vapor Presure | 1.2 x l0-4 mPa (25 °C) |
Appearance | Solid |
Merck | 13,3166 |
BRN | 2162461 |
pKa | 8.78±0.46(Predicted) |
Storage Condition | 0-6°C |
Physical and Chemical Properties | Pure white crystals, m.p.230 ~ 232 °c. The relative density is 1.56, and the vapor pressure is 1.32 × 10-5pa (50 ° C.). Soluble in acetonitrile, dimethyl sulfoxide, soluble in ethyl acetate, ethanol, dichloromethane, slightly soluble in ether, benzene, petroleum ether, acetone solubility of 6.5g/L, in water for 0.1mg/L. Light, Heat more stable, stable storage at room temperature, alkali or acid easily decomposed, can be decomposed by soil microorganisms. Industrial products are white to light yellow crystals, m.p.210 ~ 230 ℃. |
Use | Used to kill armyworm on corn and wheat |
Risk Codes | 50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | 3077 |
WGK Germany | 2 |
RTECS | YS6200000 |
Hazard Class | 9 |
Packing Group | III |
Toxicity | LD50 in mice, rats (formulation with 50% kaolin) (g/kg): 4.64, >10 orally (Mulder, Gijswijt) |
pure white crystals, melting point 230~232 deg C. The original drug (more than 95%) is white to light yellow crystals, the melting point is 210~230. The relative density is 1. 56 and the vapor pressure (50 ℃) is 1.32 × 10-s Pa. Soluble in acetonitrile, dimethyl sulfoxide, soluble in ethyl acetate, ethanol dichloromethane. Slightly soluble in ether, benzene, petroleum ether, water solubility (20 C) about 0.2 x 10-6. Stable to light and heat, stable storage at room temperature, easy to decompose in case of alkali or strong acid, and can be decomposed by soil microorganisms.
2,6-= fluorobenzonitrile is prepared from 2,6-= chlorobenzonitrile in the presence of solvent and potassium fluoride, and is hydrolyzed at 65-70 ℃ in the presence of sulfuric acid to prepare 2,6-= fluoroaniline, and then with 4 chlorophenyl isocyanate reaction can be prepared dicarbamide. Alternatively, 2,6-= fluorobenzamide is reacted with phosgene to produce 2,6-= fluorophenyl isocyanate, which is then added to p-chloroaniline to produce dimethuron.
benzoylurea insecticides. Can inhibit the synthesis of chitin in insects. The main effect is gastric toxicity, and has the effect of killing. The residual period is longer, but the efficacy is slow. For the prevention and control of Lepidoptera a variety of pests, especially on the larvae of the effect is better, the crops, natural enemies safety. Such as the prevention and control of diamondback moth, beet armyworm, Spodoptera litura, etc., in the egg incubation period to 1~2 instar larvae, with 25% suspension 500~1000 times liquid spray. Control of corn borer, corn iron beetle, in the early larval incubation period or spawning peak, with 20% suspension of 1000 to 2000 times the liquid spray, can kill eggs and larvae. Control of armyworm, in the larval peak period, with 20% per hectare of suspension 75 ~ 150g into the water spray 750kg. Prevention and Control of citrus leaf moth, in the early stage of shooting, egg incubation period, with 25% suspension 2000 times liquid spray. It can also be used for the prevention and control of picrophagia pear, Dendrolimus punctatus, poisonous moth, leaf roller, etc.
The oral LD50 of the original drug on rats and mice was greater than 4640mg/kg, the percutaneous LD50 of rabbits was> 2000mg/kg, and the inhalation LCso was> 300mg/L. It has mild irritation to clear eyes and skin of rabbits. The oral no-effect dose in rats was 125mg/kg per day. No teratogenic and mutagenic effects were observed in the experimental dose. Low toxicity to birds, quail acute oral LD50>4640mg/kg. Salmon LC50 0.3mg/L(30d).