Dexamethasone EP Impurity D
9β,11β-epoxy-17,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
CAS: 24916-90-3
Molecular Formula: C22H28O5
Dexamethasone EP Impurity D - Names and Identifiers
| Name | 9β,11β-epoxy-17,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione |
| Synonyms | 8DM 16a-MethylEpoxide 16-beta Methyl Epoxide 16α-Methyl epoxide(8-DM) Desoximetasone Impurity D Dexamethasone EP Impurity D (4aS,4bS,5aS,6aS,7R,8R,9aS,9bS) 5-(2,3-dichlorophenyl)azo-4,6-dimethyl-2-pyrimidinamine 17,21-dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione 9β,11β-epoxy-17,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione (9b,11b,16a)-9,11-epoxy-17,21-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione Desoximetasone Impurity D (Dexamethasone EP Impurity D, Mometasone Furoate EP Impurity L) Dexamethasone EP Impurity D (Mometasone Furoate EP Impurity L, Desoximetasone Impurity D) |
| CAS | 24916-90-3 |
| EINECS | 246-529-2 |
| InChI | InChI=1/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)22(15)18(27-22)10-20(16,3)21(12,26)17(25)11-23/h6-7,9,12,15-16,18,23,26H,4-5,8,10-11H2,1-3H3 |
Dexamethasone EP Impurity D - Physico-chemical Properties
| Molecular Formula | C22H28O5 |
| Molar Mass | 372.45 |
| Density | 1.32 |
| Melting Point | 210-220°C |
| Boling Point | 564.9±50.0 °C(Predicted) |
| Flash Point | 198°C |
| Solubility | Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Sonicated), Methanol ( |
| Vapor Presure | 4.09E-15mmHg at 25°C |
| Appearance | Solid |
| Color | White to Pale Yellow |
| pKa | 12.56±0.70(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.616 |
| Physical and Chemical Properties | Crystalline compound, melting point 210-220 °c. |
Dexamethasone EP Impurity D - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.685 ml | 13.425 ml | 26.849 ml |
| 5 mM | 0.537 ml | 2.685 ml | 5.37 ml |
| 10 mM | 0.268 ml | 1.342 ml | 2.685 ml |
| 5 mM | 0.054 ml | 0.268 ml | 0.537 ml |
Last Update：2024-01-02 23:10:35
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View History
Dexamethasone EP Impurity D
2-Pyridinecarboxamide, 4-chloro-N,N-bis(1-methylethyl)-
1-(4-(4-溴苯氧基)丁基)-4-甲基哌嗪
1H-Imidazolium, 1-decyl-3-(phenylmethyl)-, chloride (1:1)
8-(2,3-DIFLUOROPHENYL)-8-OXOOCTANOIC ACID
Aids004771
N-(9-OXO-9H-THIOXANTHEN-2-YL)-3-(TRIFLUOROMETHYL)BENZENECARBOXAMIDE
1,1'-联萘-8,8'-二甲酸
1-(3-ethoxypropyl)-3-[(4-methoxyphenyl)methyl]thiourea
5beta,9betaH,10alpha-Labda-8(20),13(16),14-trien-18-oic acid, 15,16-ep oxy-, methyl ester
2-Pyridinecarboxamide, 4-chloro-N,N-bis(1-methylethyl)-
1-(4-(4-溴苯氧基)丁基)-4-甲基哌嗪
1H-Imidazolium, 1-decyl-3-(phenylmethyl)-, chloride (1:1)
8-(2,3-DIFLUOROPHENYL)-8-OXOOCTANOIC ACID
Aids004771
N-(9-OXO-9H-THIOXANTHEN-2-YL)-3-(TRIFLUOROMETHYL)BENZENECARBOXAMIDE
1,1'-联萘-8,8'-二甲酸
1-(3-ethoxypropyl)-3-[(4-methoxyphenyl)methyl]thiourea
5beta,9betaH,10alpha-Labda-8(20),13(16),14-trien-18-oic acid, 15,16-ep oxy-, methyl ester