Name | Colloidal Bismuth Pectin |
Synonyms | Colloidal Bismuth ColloidalBismuthPectin Colloidal Bismuth Pectin |
CAS | 2034-00-2 |
This product is a complex of pectin and bismuth. Pectic bismuth should be between 14.0% and 16.0%, calculated as bismuth (Bi).
take this product 50mg, add water 50ml, shake, according to the law (General 0631),pH value should be 8.5~10.5.
take 0.25g of this product, put it in a measuring cylinder with 100ml plug, add water to 100ml, shake it strongly for 1 min to form a colloidal solution, and let it stand for 1 hour, the top surface of the colloidal substance must not fall below the 97ML scale.
take 2.0g of this product, add 6mL of hydrochloric acid, stir to completely wet, add water to 100ml, shake, filter, take 50ml of filtrate, divided into two parts, add 5ml of 25% barium chloride solution in one portion, place for 10 minutes, filter repeatedly until the filtrate is clear, add 4.0ml of standard potassium sulfate solution, shake well, place for 10 minutes as control solution; add 5ml of 25% barium chloride solution to the other portion, add appropriate amount of water to the same volume as the control solution, shake well, and place for 10 minutes. If turbidity occurs, it should not be more concentrated (0.08%) compared with the control solution.
take 50mg of this product, add 100ml of water and stir, filter, take 20ml of filtrate, add 2ml of p-aminobenzenesulfonic acid-a-naphthylamine solution and 10mg of zinc powder, place for 15 minutes, such as color, with standard potassium nitrate solution (precision weigh 105 mg potassium nitrate dried at 81.5°C to constant weight, put it in a 50ml measuring flask, add water to dissolve, dilute to the scale, shake well, take 5ml with precision, in a 100ml measuring flask, dilute to the scale with water and shake. Each 1 ml is equivalent to 0.3% mg of NO3) ml of control solution prepared by the same method should not be deeper ().
take this product l.Og, place in the crucible, slowly cauterize until complete carbonization, cool, add 0.5~1 ml sulfuric acid, heat with small fire until the sulfuric acid vapor is removed, burn at 600°C to completely ash, let it cool, dissolve Dropwise with l-6 ml of nitric acid, evaporate to dryness on a water bath, add 5ml of potassium hydroxide solution (), stir well, boil for 2 minutes, let it cool, add additional water to the original amount, filter, wash the residue with water, combine the washing solution with the filtrate, adjust the pH value to 7 with acetic acid, add 2ml of acetate buffer (pH 3.5), dilute to 25ml with water, add 2ml of thioacetamide solution, shake well, place for 2 minutes. If the color is developed, it shall not be deeper (0.002%) compared with the control solution of standard lead solution made by the same method.
take l.Og of this product, add 5ml hydrochloric acid and water 23mr to dissolve, check according to law (General rule 0822 first law), should comply with the provisions (0.0002%).
take 0.5g of this product, precision weighing, add nitric acid solution (1-2)5ml, heat to dissolve, then add water 150ml and Xylenol Orange indicator solution 2 drops, use B. Diamine tetraacetic acid disodium titration solution (0.05mol/L) titration solution to yellow. Per 1 ml of disodium ethylenediaminetetraacetate titration solution (0.05mol/L) corresponds to 10.45mg of bismuth (Bi).
gastric mucosal protective drugs.
light shielding, sealed storage.
This product contains bismuth pectin to bismuth (Bi) calculation, should be the label amount of 90.0% ~ 110.0%.
The content of this product is yellow granules or powder.
take the content of this product, according to the colloidal bismuth pectin under the identification test, showed the same results.
should comply with the relevant provisions under the capsule (General rule 0103).
The contents under the item of loading amount difference were mixed uniformly, and an appropriate amount (corresponding to about 75mg of bismuth) was accurately weighed and measured according to the method under the item of colloidal bismuth pectin.
colloidal bismuth pectin.
by Bi (l)40mg (2)50mg
light shielding, sealed storage.