Ciwujiano side C3
Ciwujiano side C3
CAS: 114906-74-0
Molecular Formula: C53H86O21
Ciwujiano side C3 - Names and Identifiers
Ciwujiano side C3 - Physico-chemical Properties
| Molecular Formula | C53H86O21 |
| Molar Mass | 1059.25 |
| Density | 1.43±0.1 g/cm3(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | White crystalline powder |
| pKa | 12.50±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Acanthopanax senticosus Acanthopanax senticosus dried rhizome. |
| In vitro study | Cell Viability Assay Cell Line: RAW264.7 cells Concentration: 10 µM, 20 µM and 40µM Incubation Time: 24 hours Result: Has no effect on cell cytotoxicity and inhibits NO production Western Blot Analysis Cell Line: RAW264.7 cells Concentration: 10 µM, 20 µM and 40µM Incubation Time: 24 hours Result: Decreases p-ERK and p-JNK expression. RT-PCR Cell Line: RAW264.7 cells Concentration: 10 µM, 20 µM and 40µM Incubation Time: 24 hours Result: Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner. |
| In vivo study | Animal Model: Mice Dosage: 0.5 mg/kg Administration: Oral administration; 0.5 mg/kg/day; 17 days Result: Reinforced object recognition memory. |
Ciwujiano side C3 - Reference Information
| biological activity | Ciwujianoside C3 is an orally active compound that can penetrate the blood-brain barrier, isolated from the leaves of acanthopanax. Ciwujianoside C3 has an anti-inflammatory effect and can enhance the recognition memory of individual mice. |
| in vitro study | Cell viabilityassay Cell Line: RAW264.7 cells Concentration: 10 µm, 20 µm and 40 μm invasion Time: 24 hours Result: Has no effect on cell cytotoxicity and intests NO production Western Blot Analysis Cell Line: RAW264.7 cells Concentration: 10 µm, 20 µm and 40 μm Incubation Time: 24 hours Result: Decreases p-ERK and p-JNK expression. RT-PCR Cell Line: RAW264.7 cells Concentration: 10 µM, 20 µM and 40µM Incubation Time: 24 hours Result: Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner. |
| Cell Line: | RAW264.7 cells RAW264.7 cells RAW264.7 cells |
| Concentration: | 10 µM, 20 µM and 40µM 10 µM, 20 µM and 40µM 10 µM, 20 µM and 40µM |
| Incubation Time: | 24 hours 24 hours 24 hours |
| Result: | Has no effect on cell cytotoxicity and inhibits NO production Decreases p-ERK and p-JNK expression. Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner. Reinforced object recognition memory. |
| in vivo study | Animal Model: Mice Dosage: 0.5 mg/kg Administration: Oral administration; 0.5 mg/kg/day; 17 days Result: informed object recognition memory. |
| Animal Model: | Mice |
| Dosage: | 0.5 mg/kg |
| Administration: | Oral administration; 0.5 mg/kg/day; 17 days |
| Chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, dried rhizomes derived from Acanthopanax senticosus. |
Last Update：2024-04-09 21:11:58
Supplier List
Spot supply
Product Name: Ciwujianoside C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Ciwujianoside C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Ciwujianoside C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Ciwujiano side C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Ciwujianoside C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Ciwujianoside C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Ciwujianoside C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Ciwujiano side C3 Visit Supplier Webpage Request for quotationCAS: 114906-74-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Ciwujiano side C3
4-4-N-苄氧羰基氨基环己酮
2,5-dichloro-4-[[4,5-dihydro-3-methyl-5-oxo-1-(4-sulphophenyl)-1H-pyrazol-4-yl]azo]benzenesulphonic acid, compound with N,N'-diphenylguanidine (1:2)
3-甲基-2-噁唑烷酮
4-{7-methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl}morpholine
嘧啶磺隆
2-Propyn-1-one, 1-cyclopentyl-3-(trimethylsilyl)-
48067-72-7
1,2-Benzenedicarboxylic acid, 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl] ester
1-甲基-4-(吡啶-3-基甲基)哌嗪
4-4-N-苄氧羰基氨基环己酮
2,5-dichloro-4-[[4,5-dihydro-3-methyl-5-oxo-1-(4-sulphophenyl)-1H-pyrazol-4-yl]azo]benzenesulphonic acid, compound with N,N'-diphenylguanidine (1:2)
3-甲基-2-噁唑烷酮
4-{7-methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl}morpholine
嘧啶磺隆
2-Propyn-1-one, 1-cyclopentyl-3-(trimethylsilyl)-
48067-72-7
1,2-Benzenedicarboxylic acid, 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl] ester
1-甲基-4-(吡啶-3-基甲基)哌嗪