Name | Chloroacetonitrile |
Synonyms | usafkf-5 USAF kf-5 oroacetonitriL CHLORACETONITRILE Chlorocyanomethane Chloroacetonitrile chlorocyanomethane 2-chloroacetonitrile chloromethyl cyanide chloroethane nitrile dichloroethanenitrile monochloroacetonitrile Monochloroacetonitrile monochloromethylcyanide monochloromethyl cyanide alpha-chloroacetonitrile Monochloromethyl cyanide |
CAS | 107-14-2 |
EINECS | 203-467-0 |
InChI | InChI=1/C2H2ClN/c3-1-2-4/h1H2 |
InChIKey | RENMDAKOXSCIGH-UHFFFAOYSA-N |
Molecular Formula | C2H2ClN |
Molar Mass | 75.5 |
Density | 1.193 g/mL at 25 °C (lit.) |
Melting Point | 38℃ |
Boling Point | 124-126 °C (lit.) |
Flash Point | 118°F |
Water Solubility | INSOLUBLE |
Solubility | Chloroform, Ethyl Acetate |
Vapor Presure | 1.78 psi ( 20 °C) |
Vapor Density | 3 (vs air) |
Appearance | Liquid |
Color | Clear colorless |
Exposure Limit | NIOSH: IDLH 14 ppm(25 mg/m3) |
BRN | 506028 |
Storage Condition | 2-8°C |
Stability | Stable, but reacts with water. Combustible. Incompatible with water, moisture, strong oxidizing agents, acids. |
Refractive Index | n20/D 1.422(lit.) |
Physical and Chemical Properties | Colorless transparent fuming liquid, irritating and irritating. melting point 38 ℃ boiling point 124~126 ℃ relative density 1.1930 refractive index 1.4202 flash point 47 ℃ solubility: soluble in alcohol and ether. |
Use | Used as a pharmaceutical Intermediate |
Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 2668 6.1/PG 2 |
WGK Germany | 3 |
RTECS | AL8225000 |
TSCA | Yes |
HS Code | 29269095 |
Hazard Class | 6.1 |
Packing Group | II |
Downstream Products | Phentolamine Mesylate |
colorless transparent fuming liquid, irritating and irritating. Melting point 38. Boiling point 124~126 ℃,127 ℃ decomposition, relative density of 1. 1930. Refractive index 4202. Flash point 47. Soluble in ethanol and ether. Toxic.
used as a raw material for organic synthesis and an analytical reagent.
with ethanol, chloroacetic acid as raw material, by esterification, amidation, dehydration and. First, chloroacetic acid was added to ethanol, and concentrated sulfuric acid was added under stirring. After heating to reflux, the stirring was stopped, the reaction was carried out for 8-10 H, and the aqueous layer was separated by filtration and water washing to obtain ethyl chloroacetate. Then in
Ethyl chloroacetate was added to ammonia water at 0~2 ℃, and the mixture was stirred for 15 min. After cooling, standing, filtering and drying, chloroacetamide was obtained. Finally, phosphorus pentoxide was added into chloroacetamide and heated for dehydration reaction to obtain crude chloroacetonitrile, which was then dried with phosphorus pentoxide and magnesium oxide and fractionated under reduced pressure to obtain a finished product.
This product is toxic and has the effect of stimulating the tear. It should be stored and transported under the hazard Code No. 84045.