Cereblon Ligand 1
2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid
CAS: 1061605-21-7
Molecular Formula: C15H12N2O7
Cereblon Ligand 1 - Names and Identifiers
Cereblon Ligand 1 - Physico-chemical Properties
| Molecular Formula | C15H12N2O7 |
| Molar Mass | 332.27 |
| Density | 1.606±0.06 g/cm3(Predicted) |
| Boling Point | 660.5±55.0 °C(Predicted) |
| Solubility | DMSO : 42 mg/mL |
| pKa | 2.95±0.10(Predicted) |
| Storage Condition | 2-8℃ |
Cereblon Ligand 1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.01 ml | 15.048 ml | 30.097 ml |
| 5 mM | 0.602 ml | 3.01 ml | 6.019 ml |
| 10 mM | 0.301 ml | 1.505 ml | 3.01 ml |
| 5 mM | 0.06 ml | 0.301 ml | 0.602 ml |
Last Update：2024-01-02 23:10:35
Cereblon Ligand 1 - Reference Information
| biological activity | Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3) is a Thalidomide-based Cereblon (CRBN) ligand that can be used to recruit CRBN proteins. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand of the protein through a connector to form a PROTACs (Proteolysis Targeting Chimera). |
| target | TargetValue CRBN () |
| Target | Value |
| Use | A ligand for E3 ubiquitin ligase in PROTAC technology. |
Last Update：2024-04-09 21:11:58
Supplier List
Spot supply
Product Name: Cereblon ligand 3; E3 ligase Ligand 3 Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Thalidomide-O-COOH Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid Request for quotation
CAS: 1061605-21-7
Tel: +86 0512-68417696
Email: chenmengqi@highfine.com
wuhao@highfine.com
merry@highfine.com
QQ: 4006286883
CAS: 1061605-21-7
Tel: +86 0512-68417696
Email: chenmengqi@highfine.com
wuhao@highfine.com
merry@highfine.com
QQ: 4006286883
Spot supply
Product Name: Thalidomide-O-COOH Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Cereblon ligand 3 Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Cereblon ligand 3; E3 ligase Ligand 3 Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Thalidomide-O-COOH Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid Request for quotation
CAS: 1061605-21-7
Tel: +86 0512-68417696
Email: chenmengqi@highfine.com
wuhao@highfine.com
merry@highfine.com
QQ: 4006286883
CAS: 1061605-21-7
Tel: +86 0512-68417696
Email: chenmengqi@highfine.com
wuhao@highfine.com
merry@highfine.com
QQ: 4006286883
Spot supply
Product Name: Thalidomide-O-COOH Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Cereblon ligand 3 Visit Supplier Webpage Request for quotationCAS: 1061605-21-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Cereblon Ligand 1
N-[3-(2,5-dihydro-5-thioxo-1H-tetrazol-1-yl)phenyl]acetamide, compound with 2,2',2''-nitrilotris[ethanol] (1:1)
4-[(3,4-dichlorophenyl)methoxy]-3-ethoxybenzoyl chloride
AURORA 7957
[2,2′-Bipyridine]-6,6′-dimethanol
2-[[4-(2-Pyridinyl)phenyl]methylene]- hydrazinecarboxylic acid-1,1-dimethylethyl ester
4-硝基苯基三氟醋酸酯
N-[3-(2,5-dihydro-5-thioxo-1H-tetrazol-1-yl)phenyl]acetamide, compound with 2,2',2''-nitrilotris[ethanol] (1:1)
4-[(3,4-dichlorophenyl)methoxy]-3-ethoxybenzoyl chloride
AURORA 7957
[2,2′-Bipyridine]-6,6′-dimethanol
2-[[4-(2-Pyridinyl)phenyl]methylene]- hydrazinecarboxylic acid-1,1-dimethylethyl ester
4-硝基苯基三氟醋酸酯