Carbonato ciclico de eritromicina a
Davercin
CAS: 55224-05-0
Molecular Formula: C38H65NO14
Carbonato ciclico de eritromicina a - Names and Identifiers
Carbonato ciclico de eritromicina a - Physico-chemical Properties
| Molecular Formula | C38H65NO14 |
| Molar Mass | 759.93 |
| Density | 1.22±0.1 g/cm3(Predicted) |
| Melting Point | >135°C (dec.) |
| Boling Point | 859.8±65.0 °C(Predicted) |
| Flash Point | 473.8°C |
| Solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| Vapor Presure | 1.91E-34mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| pKa | 13.49±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.534 |
| In vitro study | Erythromycin is used in treatment of respiratory, gastrointestinal, and genital tract infections, as well as skin and soft tissue infections. Erythromycin, with its ten chiral centers and two sugar substituents (L-cladinose and D-desosamine), is a good starting point for numerous medicinal chemistry efforts for improvement of its biological profile (better activity, higher stability, and improved bioavailability) since the first generation of macrolides, which had low toxicity and good tolerability, are unstable in acidic media, had low toxicity and good tolerability. |
Carbonato ciclico de eritromicina a - Risk and Safety
| Toxicity | LD50 oral in rat: 5800mg/kg |
Carbonato ciclico de eritromicina a - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.316 ml | 6.58 ml | 13.159 ml |
| 5 mM | 0.263 ml | 1.316 ml | 2.632 ml |
| 10 mM | 0.132 ml | 0.658 ml | 1.316 ml |
| 5 mM | 0.026 ml | 0.132 ml | 0.263 ml |
Last Update：2024-01-02 23:10:35
Carbonato ciclico de eritromicina a - Introduction
Davercin is a broad-spectrum antibiotic, which belongs to the macrolide family of antibiotics. Its chemical name is 9-{O-[(2-{[4-{[(2-{[2-{[(4-{[(2-{[(1R,2R,3S,4S,6R,8R,10R,11R,12S,13S,15s, 17s)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-] oxy}-1-hydroxyethyl)-] toxy}-5-ethyl-1, 3,4-oxopentan-2-yl] oxy 15-hydroxy-13-methyl-1,5,7,9,14,] oxy}-6-methyll-1-oxobicyclo [11.2.1]hexadec-7-en-17-yl]carbonyl}-11,12-dihy droxy-4-[(2S,4R)-8-methoxy-1-methylethyl]-3,6,10,12,14, 16-hexaoxohexecan-1-yl} nonadecan-21-oate.
Davercin has excellent anti-biological activity and can inhibit the growth of a variety of bacteria. It is mainly used in clinical treatment of a variety of infectious diseases, such as respiratory tract infection, skin and soft tissue infection, ear, nose and throat infection. In addition, Davercin can also be used to treat gastrointestinal infections and sexually transmitted diseases.
The preparation of Davercin is generally obtained by reacting erythromycin with a cyclic ester group. Specific preparation methods include esterification reaction, complexation reaction, etc.
Davercin has excellent anti-biological activity and can inhibit the growth of a variety of bacteria. It is mainly used in clinical treatment of a variety of infectious diseases, such as respiratory tract infection, skin and soft tissue infection, ear, nose and throat infection. In addition, Davercin can also be used to treat gastrointestinal infections and sexually transmitted diseases.
The preparation of Davercin is generally obtained by reacting erythromycin with a cyclic ester group. Specific preparation methods include esterification reaction, complexation reaction, etc.
Last Update：2024-04-09 20:52:54
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CAS: 55224-05-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Multiple SpecificationsSpot supply
Product Name: Erythromycin Cyclocarbonate Visit Supplier Webpage Request for quotationCAS: 55224-05-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Davercin Visit Supplier Webpage Request for quotationCAS: 55224-05-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Erythromycin Cyclocarbonate Visit Supplier Webpage Request for quotationCAS: 55224-05-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Davercin Visit Supplier Webpage Request for quotation
CAS: 55224-05-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 55224-05-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
Carbonato ciclico de eritromicina a
2-(3-(三氟甲基)吡啶-2-基)乙酸
5-氯噻吩-2-磺酰L 氯
1-{7-[(E)-2-(二甲基氨基)乙烯基]-2-苯基[1,2,4]三唑并[1,5-A]嘧啶-6-基}乙酮
3-([[(2-CARBOXYETHYL)THIO]METHYL]THIO)PROPANOIC ACID
13C7-展青霉素
2-(3-(三氟甲基)吡啶-2-基)乙酸
5-氯噻吩-2-磺酰L 氯
1-{7-[(E)-2-(二甲基氨基)乙烯基]-2-苯基[1,2,4]三唑并[1,5-A]嘧啶-6-基}乙酮
3-([[(2-CARBOXYETHYL)THIO]METHYL]THIO)PROPANOIC ACID
13C7-展青霉素