CELLSTAIN- HOECHST 33342 SOLUTION
2'-(4'-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bis-1H-benzimidazole trihydrochloride trihydrate
CAS: 23491-52-3
Molecular Formula: C27H28N6O
CELLSTAIN- HOECHST 33342 SOLUTION - Names and Identifiers
| Name | 2'-(4'-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bis-1H-benzimidazole trihydrochloride trihydrate |
| Synonyms | Ho 342 Hoe 33342 Bisbenzimide Hoechst 33342 bis-benzimide (ethoxyphenyl form) CELLSTAIN- HOECHST 33342 SOLUTION 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole 2,5'-Bibenzimidazole, 2'-(p-ethoxyphenyl)-5-(4-methyl-1-piperazinyl) 2,5'-Bibenzimidazole, 2'-(p-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)- 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-5'-bi-1h-benzimidazole 2,5-Bi-1H-benzimidazole, 2-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)- 2'-(4-ethoxyphenyl)-6-(4-methylpiperazin-1-yl)-1H,3'H-2,5'-bibenzimidazole 2,5'-Bi-1H-benzimidazole, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)- (9CI) 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzimidazole trihydrochloride 2'-(4'-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bis-1H-benzimidazole trihydrochloride trihydrate bisBenzimide, HOE 33342, Hoechst 33342, 2μ-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5μ-bi-1H-benzimidazole trihydrochloride |
| CAS | 23491-52-3 |
| EINECS | 245-691-1 |
| InChI | InChI=1/C27H28N6O.3ClH/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33;;;/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31);3*1H |
CELLSTAIN- HOECHST 33342 SOLUTION - Physico-chemical Properties
| Molecular Formula | C27H28N6O |
| Molar Mass | 452.55 |
| Density | 1.274±0.06 g/cm3(Predicted) |
| Boling Point | 725.9±70.0 °C(Predicted) |
| Solubility | Soluble in water |
| Appearance | Yellow or yellow-green powder |
| BRN | 1234011 |
| pKa | 10.97±0.10(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD00012678 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | Hoechst 33342 binds to adenine-thymine-rich regions of DNA in the minor groove. On binding to DNA, the fluorescence greatly increases. This protocol describes the use of Hoechst 33342 to label nuclear DNA of cells grown in culture. Hoechst 33342 can also be used to stain fixed cells by substituting Hoechst 33342 for DAPI. |
CELLSTAIN- HOECHST 33342 SOLUTION - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R37 - Irritating to the respiratory system R35 - Causes severe burns |
| Safety Description | S22 - Do not breathe dust. S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| RTECS | DT4200000 |
| FLUKA BRAND F CODES | 3-8-10 |
| HS Code | 32129000 |
| Toxicity | dni-hmn-hla 300 nmol/L CRNGDP 13,2389,1992 |
CELLSTAIN- HOECHST 33342 SOLUTION - Reference
| Reference Show more | 1. Xu Yixiao, He Xilin, Zhang Teng, Zhao Zhijuan, Wei Guangling. Molecular Identification of Red Red Tide Algae in Weizhou Island of Beibu Gulf [J]. Marine Science, 2020,44(09):63-73. 2. [IF = 6.15] Zhou Jing-si et al."NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation." Acta Pharmacol Sin. 2018 May;40(2):180-191 3. [IF = 5.582] Shuai Li et al."Phosphorylcholine micelles decorated by hyaluronic acid for enhancing antitumor efficiency." Polym Chem-Uk. 2017 Apr;8(16):2472-2483 4. [IF = 4.268] Ramachandran Vinayagam et al."7, 8-Dihydroxycoumarin (daphnetin) protects INS-1 pancreatic β-cells against streptozotocin-induced apoptosis." Phytomedicine. 2017 Jan;24:119 5. [IF = 5.162] Huibin Dong et al."Polysaccharide SAFP from Sarcodon aspratus attenuates oxidative stress-induced cell damage and bleomycin-induced pulmonary fibrosis." Int J Biol Macromol. 2020 Dec;164:1215 |
CELLSTAIN- HOECHST 33342 SOLUTION - Introduction
Commonly used reagents for cytogenetic research, fluorescence staining of cell DNA, insertion into the A- T region of DNA, have low cytotoxicity and form membrane-permeable fluorescent DNA chains.
Last Update：2022-10-16 17:15:08
CELLSTAIN- HOECHST 33342 SOLUTION - Reference Information
| biological activity | Hoechst 33342 (Pibenzimol, bisBenzimide H 33342, HOE 33342, HO342) is a membrane-permeable fluorescent stain that can stain living cells. Hoechst 33342 can bind to small grooves of adenine-thymine-rich regions of DNA. |
| Target | Value |
| Uses | Commonly used reagents for cytogenetic research, used for staining DNA, chromosomes and nuclei. Can be used in fluorescence microscopy or flow cytometry. Excitation max. = 346 nm Emission max. = 460 nm |
Last Update：2024-04-10 22:29:15
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View History
CELLSTAIN- HOECHST 33342 SOLUTION
二(4,5-二氢萘并[1,2-D])四硫富瓦烯
1-Tridecanol, 2-undecyl-
tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine...
5-氰基-7-(三氟甲基)-1,2,3,4-四氢喹啉盐酸盐
乙酰基-D-3-(2-萘基)丙氨酸
1-(丙烷-1-磺酰)哌啶-4-胺盐酸
鯨蠟醇
Oxiranecarboxamide, 3-(1-oxobutyl)-, (1R-cis)- (9CI)
环己基(4-甲基苯基)甲酮
二(4,5-二氢萘并[1,2-D])四硫富瓦烯
1-Tridecanol, 2-undecyl-
tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine...
5-氰基-7-(三氟甲基)-1,2,3,4-四氢喹啉盐酸盐
乙酰基-D-3-(2-萘基)丙氨酸
1-(丙烷-1-磺酰)哌啶-4-胺盐酸
鯨蠟醇
Oxiranecarboxamide, 3-(1-oxobutyl)-, (1R-cis)- (9CI)
环己基(4-甲基苯基)甲酮