Name | Bromoadiolone |
Synonyms | RATOBAN SUPER CAID SUPER-ROZOL Bromadiolone Bromoadiolone (hydroxy-4coumarinyl3)-3phenyl-3(bromo-4biphenylyl-4)-1propanol-1 1'-biphenyl)-4-yl)3-hydroxy-1-phenylpropyl)-4-hydroxy-2h-1-3-(3-(4'-bromo( 2h-1-benzopyran-2-one,3-(3-(4'-bromo(1,1'-biphenyl)-4-yl)-3-hydroxy-1-phenylp 2h-1-benzopyran-2-one,3-(3-(4`-bromo-(1,1`-biphenyl)-4-yl)-3-hydroxy-1-phenylp (hydroxy-4-coumarinyl-3)-3-phenyl-3-(bromo-4-biphenylyl-4)-1-propanol-1(french 3-[3-(4'-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-chromen-2-one 3-[3-(4'-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-2-hydroxy-4H-chromen-4-one |
CAS | 28772-56-7 |
EINECS | 249-205-9 |
InChI | InChI=1/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2 |
Molecular Formula | C30H23BrO4 |
Molar Mass | 527.41 |
Density | 1.3243 (rough estimate) |
Melting Point | 200-210° |
Boling Point | 723.4±60.0 °C(Predicted) |
Flash Point | 391.282°C |
Water Solubility | 19 mg l-1 (20 °C) |
Vapor Presure | 2 x l0-6Pa (20 °C) |
Appearance | Powder |
Merck | 13,1366 |
BRN | 1335336 |
pKa | 4.04(at 21℃) |
Storage Condition | -20°C |
Refractive Index | 1.4490 (estimate) |
Physical and Chemical Properties | The original drug was yellow powder. m. P. 200-210 °c, vapor pressure 1.78 x 10-5PA (70 °c). 20 C solubility: dimethyl amide 730g/L, ethyl acetate 25g/L, ethanol 8.2g/L, Water 19mg/L. Stable under normal conditions. |
Use | Used for urban and rural, residential, hotel, restaurant, warehouse, field and other environmental rodent control |
Risk Codes | R27/28 - R50 - Very Toxic to aquatic organisms |
Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 2811 |
WGK Germany | 3 |
RTECS | GN4934700 |
Hazard Class | 6.1(a) |
Packing Group | I |
Toxicity | LD50 in rats, mice (mg/kg): 1.125, 1.75 orally (Grand) |
Raw Materials | 4-Hydroxycoumarin Benzaldehyde 4-Bromobiphenyl Biphenyl Potassium borohydride Coumarin Bromine Ethylene glycol Acetyl Chloride |
The original drug was yellow powder. The melting point is 200-210 °c and the vapor pressure (70 °c) is 1.78 x 10-5Pa. 20~25 ° C solubility:(g/L): dimethylamide 730.0, ethyl acetate 25.0, acetone 22.3, chloroform 10.1, ethanol 8.2, methanol 5.6, hexane 0.2, water 0. 019.
after mixing the quantitative bromobiphenyl, catalyst and solvent, acetic anhydride is added dropwise at a certain temperature, heated to reflux for several hours, and the solvent is distilled off, the residue is transferred to a hydrolysis flask containing an acid solution and subjected to hydrolysis to obtain acetyl-p-bromobiphenyl. 3-{ 2-[P-(p-bromophenyl) benzoylmethyl] benzyl) was prepared from the product obtained by condensation of the product with benzaldehyde and the like and then reacted with 4-hydroxycoumarin. A 4 hydroxy coumarin. Finally, the compound, the reducing agent and the solvent are put into the reaction bottle, stirred, heated, and reacted with isopropyl alcohol, hydrolyzed, filtered, washed and dried to obtain the crude product, and then acidified to obtain bromadiolone.
The second generation anticoagulant rodenticide, good palatability, strong toxicity, high efficiency and broad spectrum, safety. It is effective in rodents that develop resistance to first-generation anticoagulants. For the control of domestic and wild rodents.
oral LD50 of rats and mice: 1. 125mg/kg, 1.75mg/kg. No obvious irritation to the skin. It is irritating to eyes. Fish LC50 3mg/L(48h), Daphnia LC50 8. 8mg/L, wild duck LD50 lOOOmg/kg, quail LD50 1690mg/kg.