Bisoprolol base
1-[isopropylamino]-3-[isopropoxyethoxymethylphenoxy]-2-propanol
CAS: 66722-44-9
Molecular Formula: C18H31NO4
Bisoprolol base - Names and Identifiers
Bisoprolol base - Physico-chemical Properties
| Molecular Formula | C18H31NO4 |
| Molar Mass | 325.44 |
| Density | 1.033±0.06 g/cm3(Predicted) |
| Melting Point | 100 °C |
| Boling Point | 445.0±45.0 °C(Predicted) |
| Water Solubility | 5.5ug/L(100 ºC) |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Appearance | neat |
| Color | Yellow |
| pKa | pKa 9.57(H2O(extrap) t=25±1 Iunde?ned Aratmosphere) (Uncertain) |
| Storage Condition | -20°C Freezer, Under Inert Atmosphere |
| Use | For the treatment of cardiovascular and cerebrovascular diseases |
Bisoprolol base - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 1 |
| RTECS | UB8380000 |
| Hazard Class | IRRITANT |
Bisoprolol base - Nature
Open Data Verified Data
Bisoprolol hemifumarate Crystal, melting point 100 °c. Soluble in ethanol.
Last Update：2024-01-02 23:10:35
Bisoprolol base - Preparation Method
Open Data Verified Data
4-[(2-isopropoxyethoxy) methyl] phenol is reacted with epichlorohydrin, and the resulting epoxide is reacted with isopropylamine to obtain Bisoprolol.
Last Update：2022-01-01 09:10:08
Bisoprolol base - Use
Open Data Verified Data
developed by E.Merock, Germany, launched in 1986. It is a β1-blocker with high affinity and selectivity for cardiac-receptors, and its β1-selectivity is higher than that of cardiac-selective β1-blockers such as Atenolol and metoprolol. No cell membrane stabilizing effect in the therapeutic dose range. It is used for hypertension and coronary heart disease, and is relatively safe for hypertensive patients with asthma.
Last Update：2022-01-01 09:10:08
Supplier List
Multiple SpecificationsSpot supply
Product Name: Bisoprolol Visit Supplier Webpage Request for quotationCAS: 66722-44-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Multiple SpecificationsSpot supply
Product Name: Bisoprolol Visit Supplier Webpage Request for quotationCAS: 66722-44-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
View History
Bisoprolol base
2-oxoglutaric acid, compound with 5-hydroxy-6-methylpyridine-3,4-dimethanol (1:2)
5-氯靛红酸酐
Ferroceneboronic acid (contains varying amounts of anhydride)
Benzyl (4-(hydroxyMethyl)bicyclo[2.2.2]octan-1-yl)carbaMate
RARECHEM AK HZ 0049
Einecs 208-182-5
METHALLYL METHACRYLATE
Jaborosalactone D
SULPHAMETHOMIDINE
2-oxoglutaric acid, compound with 5-hydroxy-6-methylpyridine-3,4-dimethanol (1:2)
5-氯靛红酸酐
Ferroceneboronic acid (contains varying amounts of anhydride)
Benzyl (4-(hydroxyMethyl)bicyclo[2.2.2]octan-1-yl)carbaMate
RARECHEM AK HZ 0049
Einecs 208-182-5
METHALLYL METHACRYLATE
Jaborosalactone D
SULPHAMETHOMIDINE