Benzeneethanethioamide, 3-(trifluoromethyl)-
2-[3-(Trifluoromethyl)phenyl]ethanethioamide
CAS: 952182-78-4
Molecular Formula: C9H8F3NS
Benzeneethanethioamide, 3-(trifluoromethyl)- - Names and Identifiers
Benzeneethanethioamide, 3-(trifluoromethyl)- - Physico-chemical Properties
| Molecular Formula | C9H8F3NS |
| Molar Mass | 219.23 |
| Melting Point | 78～80℃ |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09817423 |
Benzeneethanethioamide, 3-(trifluoromethyl)- - Introduction
2-[3-(Trifluoromethyl)phenyl]ethanethioamide(2-[3-(Trifluoromethyl)phenyl]ethanethioamide) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-Molecular formula: C10H9F3N2S
-Molecular weight: 254.25g/mol
-Melting point: about 70-71°C
-Boiling Point: No clear data
-Solubility: Slightly soluble in water, soluble in organic solvents such as ether and dichloromethane
Use:
- 2-[3-(Trifluoromethyl)phenyl]ethanethioamide has a wide range of applications in organic synthesis. It can be used as a catalyst and ligand to participate in various organic reactions, such as coupling reactions, reduction reactions and cyclization reactions.
-It can also be used as an important intermediate and play an important role in the synthesis of drugs and pesticides.
Preparation Method:
- 2-[3-(Trifluoromethyl)phenyl]ethanethioamide can be synthesized by the following methods:
1. First, 2-bromoethylthioamide is reacted with 3-(trifluoromethyl) phenyl magnesium halide to obtain the corresponding substituted product.
2. Then, the substitution product is subjected to an amidation reaction, using an appropriate reagent, such as trimethyloxysilylamine or thiomethyldimethylamine chloride.
Safety Information: The safety of
- 2-[3-(Trifluoromethyl)phenyl]ethanethioamide has not been fully evaluated. It is an organic compound with potential effects on health and the environment.
-When handling the compound, care should be taken to follow appropriate laboratory safety practices, including wearing appropriate protective equipment and handling in a well-ventilated area.
-Avoid contact with skin, eyes and mucous membranes during use or handling. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-In addition, the compound should be stored in a sealed container and away from fire and oxidizing agents.
Nature:
-Appearance: White solid
-Molecular formula: C10H9F3N2S
-Molecular weight: 254.25g/mol
-Melting point: about 70-71°C
-Boiling Point: No clear data
-Solubility: Slightly soluble in water, soluble in organic solvents such as ether and dichloromethane
Use:
- 2-[3-(Trifluoromethyl)phenyl]ethanethioamide has a wide range of applications in organic synthesis. It can be used as a catalyst and ligand to participate in various organic reactions, such as coupling reactions, reduction reactions and cyclization reactions.
-It can also be used as an important intermediate and play an important role in the synthesis of drugs and pesticides.
Preparation Method:
- 2-[3-(Trifluoromethyl)phenyl]ethanethioamide can be synthesized by the following methods:
1. First, 2-bromoethylthioamide is reacted with 3-(trifluoromethyl) phenyl magnesium halide to obtain the corresponding substituted product.
2. Then, the substitution product is subjected to an amidation reaction, using an appropriate reagent, such as trimethyloxysilylamine or thiomethyldimethylamine chloride.
Safety Information: The safety of
- 2-[3-(Trifluoromethyl)phenyl]ethanethioamide has not been fully evaluated. It is an organic compound with potential effects on health and the environment.
-When handling the compound, care should be taken to follow appropriate laboratory safety practices, including wearing appropriate protective equipment and handling in a well-ventilated area.
-Avoid contact with skin, eyes and mucous membranes during use or handling. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-In addition, the compound should be stored in a sealed container and away from fire and oxidizing agents.
Last Update：2024-04-09 21:01:54
