BUPRENORPHINE BASE

Name	Buprenorphine
Synonyms	rx6029m Buprenex CL-112302 BUPRENORPHINE BUPRENORPHINE BASE l)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-,(5-alpha,7-alpha 6,14-ethenomorphinan-7-methanol,17-(cyclopropylmethyl)-alpha-(1,1-dimethylethy [5a,7a(S)]-17-(Cyclopropylmethyl)-a-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-a-methyl-6,14-ethenomorphinan-7-methanol Hydrochloride
CAS	52485-79-7
EINECS	257-950-6

Molecular Formula	C29H41NO4
Molar Mass	467.65
Density	1.0953 (rough estimate)
Melting Point	260-262°C
Boling Point	570.1°C (rough estimate)
Flash Point	9℃
Solubility	Very slightly soluble in water, freely soluble in acetone, soluble in methanol, slightly soluble in cyclohexane. It dissolves in dilute solutions of acids.
pKa	pKa 8.24(H2O t=23.0±0.3) (Uncertain)
Storage Condition	-20°C
Refractive Index	1.6290 (estimate)

Risk Codes	R11 - Highly Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R39/23/24/25 -
Safety Description	S16 - Keep away from sources of ignition. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S7 - Keep container tightly closed.
UN IDs	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
Toxicity	LD50 oral in mouse: 260mg/kg

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