Molecular Formula | C184H295N69O42R2S |
Molar Mass | 4177.8132 |
Water Solubility | Soluble in water at 1mg/ml |
Appearance | Lyophilized powder |
Storage Condition | -15°C |
biological activity | Apelin-36(human) is an endogenous orphan G protein-coupled receptor APJ agonist, the EC50 was 20 nM. Apelin-36(human) has a high affinity for the human APJ receptor expressed by HEK 293 cells (pIC50 = 8.61). Apelin-36(human) is associated with two major biological activities: cardiovascular and metabolic. Apelin-36(human) inhibited entry of HIV-1 and HIV-2 into APJ-expressing NP2/CD4 cells. |