ALCLOMETHASONE DIPROPIONATE
Alclometasone
CAS: 67452-97-5
Molecular Formula: C22H29ClO5
ALCLOMETHASONE DIPROPIONATE - Names and Identifiers
ALCLOMETHASONE DIPROPIONATE - Physico-chemical Properties
| Molecular Formula | C22H29ClO5 |
| Molar Mass | 408.919 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Melting Point | 176-179° |
| Boling Point | 607.1±55.0 °C(Predicted) |
| Specific Rotation(α) | D26 +47.5° (c = 0.3 in DMF) |
| pKa | 12.30±0.70(Predicted) |
| In vivo study | The prodrug of alclometasone is alclometasone dipropionate.Alclometasone dipropionate (subcutaneous injection; 1 % (w/v) arabic gum; 2 weeks) inhibits the activity of androgen-dependent cytochrome P450 and O-depropylation activity as a dose-dependent manner in male Slc-Wistar strain rats. However, it has no effects on hepatic drug metabolism in female rats or DS strain mice. |
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Product Name: 7a-Chloro-16a-methyl prednisolone Visit Supplier Webpage Request for quotationCAS: 67452-97-5
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