Name | α-Bromo-4-nitroacetophenone |
Synonyms | ASISCHEM D48949 AKOS BBS-00003952 4-NITROPHENACYL BROMIDE 4'-NITROPHENACYL BROMIDE α-Bromo-4-nitroacetophenone A-BROMO-P-NITROACETOPHENONE 2-Bromo-4-nitroacentophenone 2-bromo-4'-nitroacetophenone 2-BROMO-4'-NITROACENTOPHENONE ALPHA-BROMO-P-NITROACETOPHENONE ALPHA-BROMO-4-NITROACETOPHENONE 2-bromo-1-(4-nitrophenyl)ethanone |
CAS | 99-81-0 |
EINECS | 202-789-9 |
InChI | InChI=1/C8H6BrNO3/c9-5-8(11)6-1-3-7(4-2-6)10(12)13/h1-4H,5H2 |
Molecular Formula | C8H6BrNO3 |
Molar Mass | 244.04 |
Density | 1.8033 (rough estimate) |
Melting Point | 94-99°C(lit.) |
Boling Point | 325.2±17.0 °C(Predicted) |
Flash Point | 150.5°C |
Vapor Presure | 0.000233mmHg at 25°C |
Appearance | Crystalline Powder |
Color | Yellow to orange |
BRN | 393567 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.6090 (estimate) |
Use | Used as raw materials for organic synthesis and pharmaceutical intermediates |
Risk Codes | R34 - Causes burns R37 - Irritating to the respiratory system |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 3261 8/PG 2 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 19 |
TSCA | Yes |
HS Code | 29147000 |
Hazard Note | Irritant |
Hazard Class | 8 |
Packing Group | III |
crystalline solid, melting point 98 °c.
It is prepared by bromination of p-nitroacetophenone. The solvent chlorobenzene and p-nitroacetophenone are added into the reaction vessel, and a small amount of bromine is added dropwise at 18 ℃, the temperature is controlled at 26~28 ℃, and bromine is added dropwise. After dropping, the reaction is carried out for 1 hour, and the temperature is raised to drive out HBr, and the post-treatment is obtained.
A pharmaceutical intermediate for the synthesis of chloramphenicol and the like.