97914-59-5 - Names and Identifiers
97914-59-5 - Physico-chemical Properties
Molecular Formula | C8H6F2O3
|
Molar Mass | 188.13 |
Density | 1.370 |
Melting Point | 98-100°C |
Boling Point | 274℃ |
Flash Point | 119℃ |
Vapor Presure | 0.00276mmHg at 25°C |
pKa | 3.11±0.36(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.496 |
MDL | MFCD00236223 |
97914-59-5 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R36 - Irritating to the eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
Hazard Note | Irritant |
97914-59-5 - Introduction
2-(Difluoromethoxy)benzoic acid, chemical formula is C8H6F2O3, molecular weight is 188.13. It is an organic compound with the following properties:
1. Appearance: White crystalline solid.
2. Melting point: 80-82°C.
3. Boiling point: 244-245°C.
4. Solubility: Soluble in organic solvents such as ether, chloroform and dimethylformamide.
2-(Difluoromethoxy)benzoic acid has a wide range of applications, mainly in the field of organic synthesis and medicine. Specific uses include:
1. as a drug intermediate: can be used for the synthesis of various drugs and bioactive molecules.
2. for coatings: can be used as additives in organic synthetic materials.
3. for electronic chemistry: can be used for the synthesis of dyes and liquid crystal molecules.
2-(Difluoromethoxy)benzoic acid is mainly prepared by the following methods:
1. In chloroform, o-benzoic acid is reacted with trifluoromethane anhydride, and then gaseous hydrogen fluoride is added.
2. react o-benzoic acid with silver nitrite to obtain p-nitrobenzoic acid, then react with bromofluoromethane, and finally treat with organic solvent to obtain 2-(Difluoromethoxy)benzoic acid.
The security information for the 2-(Difluoromethoxy)benzoic acid is as follows:
1. allergenicity: there may be allergic reactions to some people, please pay attention to protective measures.
2. ignition: with a certain degree of ignition, please stay away from the source of fire.
3. inhalation: may cause respiratory irritation, please avoid inhalation.
4. swallowing: may cause gastrointestinal irritation, please avoid eating.
5. contact: may cause skin and eye irritation, please avoid contact.
When using 2-(Difluoromethoxy)benzoic acid, please refer to the product manual and operate in strict accordance with the operating specifications and safety operations. In the event of an accident, seek medical help immediately.
Last Update:2024-04-09 21:54:55