Acid is an organic compound whose chemical formula is C6H7BClNO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: acid is a white to light yellow solid.
-Solubility: Soluble in some organic solvents, such as chloroform, methanol and dimethyl sulfoxide.
-Melting point: about 152-155°C.
Use:
-must acid is an important organic synthesis intermediate, which is widely used in the synthesis of drugs, pesticides and other organic compounds. It is commonly used as a boronic acid coupling reagent in Suzuki reactions, reacting with aryl or alkynyl halides to produce the corresponding aryl or alkynyl boronic esters.
Preparation Method:
-the acid can be synthesized by the following steps:
1. 3-Chloro-2-methoxypyridine was taken as the starting material.
2. The starting material is reacted with phenylboronic acid, and the reaction is carried out in the presence of a base.
3. After the reaction and purification steps, acid is obtained.
Safety Information:
-must acid no obvious danger under normal operating conditions. However, in any laboratory operation, proper laboratory safety measures should be observed.
-Avoid contact with skin and eyes during operation, and use appropriate personal protective equipment, such as laboratory gloves, safety glasses and external laboratory ventilation.
-If you come into contact with the compound or breathe its dust, wash the affected area immediately and seek medical help.