954229-57-3 - Names and Identifiers
954229-57-3 - Physico-chemical Properties
954229-57-3 - Introduction
5-(3-bromophenyl)-3-methylisoxazole is an organic compound with the following properties:
1. Appearance: colorless or yellowish solid.
2. Solubility: Soluble in organic solvents such as chloroform, ether and dimethylformamide, insoluble in water.
3. melting point: about 86-88 ℃.
The main use of this compound is as a pharmaceutical intermediate and a starting material for organic synthesis. It can be used to synthesize a variety of biologically active compounds, such as pesticides, anticancer drugs, etc.
The method for preparing 5-(3-bromophenyl)-3-methylisoxazole is as follows:
First, 3-bromobenzoic acid and sodium alkoxide are subjected to an esterification reaction to obtain 3-bromobenzoic acid ester. The resulting ester is then subjected to a nucleophilic substitution reaction with methylisoxazolone to yield 5-(3-bromophenyl)-3-methyllioxazole under basic conditions.
Safety information regarding this compound should be handled with caution. It may be irritating to the skin, eyes and respiratory tract and contact must be avoided. In the process of use, should wear appropriate protective measures, such as gloves, goggles and protective mask. Avoid inhaling its vapors or dust. When using or storing, it is necessary to keep away from fire and heat sources, and maintain a well-ventilated place. In case of accident or discomfort, seek medical attention immediately.
Last Update:2024-04-09 21:54:55