945553-94-6 - Names and Identifiers
945553-94-6 - Physico-chemical Properties
Molecular Formula | C20H12ClFN4O4S
|
Molar Mass | 458.8500832 |
Storage Condition | 2-8℃ |
945553-94-6 - Introduction
4-(3-Chloro-4-fluoroaniline)-phosphino-4-phosphino-phosphino-4 (also known as 4-(3-chloro-4-fluoroaniline)-7-benzenesulfonyl-6-nitroquinazoline) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless or yellowish crystal
-Molecular formula: C20H11ClF2N4O4S
-Molecular weight: 472.84g/mol
-melting point: 300-304 degrees Celsius
-Solubility: better solubility in some organic solvents
Use:
- 4-(3-Chloro-4-fluoroaniline)-is a quinazoline anticancer drug intermediate, which can inhibit tumor growth and protease activity.
-It can be used for research and development of new anti-cancer drugs.
Method:
The synthesis of
- 4-(3-Chloro-4-fluoroaniline)-is mainly completed by a series of organic synthesis reactions, including the ammoniacal salt of aniline under acidic conditions, and then the reaction with 7-benzenesulfonyl-6-nitroquinazoline, and finally the target product is obtained by reduction and crystallization purification.
Safety Information:
- 4-(3-Chloro-4-fluoroaniline)-is an organic compound with certain toxicity. Therefore, in handling and storage, it is necessary to follow the relevant safety procedures.
-Take care to avoid direct contact with skin and eyes, and wear protective glasses and gloves if necessary.
-When preparing and using the compound in the laboratory, it should be carried out in a well-ventilated environment to avoid inhaling its gas or dust.
-The specific hazards and risks of this compound deserve further evaluation and research. Therefore, it is recommended to conduct a comprehensive safety assessment and refer to relevant literature before using this compound.
Last Update:2024-04-09 20:48:19