Name | 6-Carboxytetramethylrhodamine |
Synonyms | 6-TAMRA (6-TAMRA) 6-CarboxytetraMethyl 6-CARBOXYTETRAMETHYLRHODAMINE 6-Carboxytetramethylrhodamine N,N,N',N'-TetraMethyl-6-carboxyrhodaMine 6-CARBOXYTETRAMETHYLRHODAMINE (SINGLE IS 6-CARBOXY-TETRAMETHYLRHODAMINE, FOR FLUORESCENCE* 6-CARBOXY-TETRAMETHYLRHODAMINE, FOR FLUORESCENCE* 9-(2,5-Dicarboxyphenyl)-3,6-bis(diMethylaMino)xanthyliuM 4-carboxy-3-[6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl]benzoate |
CAS | 91809-67-5 |
InChI | InChI=1/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31) |
Molecular Formula | C25H22N2O5 |
Molar Mass | 430.45 |
Melting Point | NA |
Water Solubility | DMSO: soluble |
Solubility | Soluble in methanol, DMSO, DMF or aqueous buffers (pH > 6.5). , Soluble in methanol |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Sensitive | `sensitive` to light and stored in air |
Use | 6-carboxytetramethylrhodamine (6-TAMRA) is used to establish fluorescent DNA probes and label proteins/peptides. The corresponding succinimide ester is a single isomer fluorophore, which is most commonly used in DNA automatic sequencing. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-10 |
HS Code | 3204 90 00 |
biological activity | 6-TAMRA is a fluorescent group of avidin derivatives widely used for the preparation of fluorescent antibodies and for immunohistochemistry. |
Use | for automated DNA sequencing; protein/peptide |