Name | Methyl cellulose |
Synonyms | MC adulsin Methocel Methylcellulose Methyl cellulose walsrodermc20000s 'TYLOSE'(R) MH 300 MODIFIED CELLULOSE 'TYLOSE'(R) MH 1000 MODIFIED CELLULOSE, MC CELLULOSE METHYL ETHER Cellulose Methyl Ether Cellulose, methyl ether Methyl cellulose, viscosity 8000 cPs (6S)-3,4,5-trimethoxy-2-(methoxymethyl)-6-[(3R)-4,5,6-trimethoxy-2-(methoxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran |
CAS | 9004-67-5 |
EINECS | 232-674-9 |
InChI | InChI=1/C12H20O10/c1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-8)17(26-6)16(14)25-5/h11-20H,9-10H2,1-8H3/t11?,12?,13?,14-,15?,16?,17?,18?,19?,20+/m1/s1 |
Molecular Formula | C20H38O11 |
Molar Mass | 454.50912 |
Density | 1.01 g/cm3(Temp: 70 °C) |
Melting Point | 290-305 °C |
Boling Point | 507°C at 760 mmHg |
Flash Point | 196.3°C |
Water Solubility | SOLUBLE IN COLD WATER |
Solubility | Soluble in glacial acetic acid, slowly soluble in cold water and expand into viscose solution, insoluble in acetone, alcohol, ether, toluene, chloroform and hot water. |
Vapor Presure | 6.67E-10mmHg at 25°C |
Appearance | White powder |
Color | White, yellow-white or grayish-white |
Merck | 14,6040 |
Storage Condition | Room Temperature |
Stability | Stable. Incompatible with strong oxidizing agents, bleach, perchloric acid, nitric acid, perchlorates, alkali nitrates, alkali nitrites, calcium oxide. |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.469 |
MDL | MFCD00081763 |
Physical and Chemical Properties | A cellulose methyl ether. White or light yellow or light gray small particles (95% through a 40-mesh sieve), filaments or powder. Odorless and tasteless. It's hygroscopic. The apparent density is 0.3~0.7g/m1. When all R in the structure is methyl, its degree of substitution is equal to 3, and the methoxy content accounts for 45.57%. Methyl cellulose used as a food additive, its methoxy content should be between 26% and 33%, and its corresponding displacement degree should be 1.7 to 2.2. When the degree of displacement is lower than 1.3, it is soluble in alkali, and when it is more than 2.6, it is soluble in organic solvent. It is soluble in cold water, pyridine, aniline, trimethylformamide, benzyl alcohol and glacial acetic acid between 1.3 and 2.6. The aqueous solution is stable at neutral and normal temperature, while at high temperature it produces gelling and precipitation. The gelling temperature depends on the viscosity and concentration of the solution, and the gelling temperature is lower when the viscosity and concentration are large. The presence of inorganic salts can increase the viscosity. Because it is a non-ionic solution, polyvalent metals cannot make it precipitate. Only when the electrolyte concentration and other dissolved substances exceed a certain limit, the gel effect will occur. The aqueous solution is surface active. After drying, it forms a thin film. After heating and cooling, it undergoes a reversible transition from sol to gel. |
Use | This product can be used as a sizing agent for textile printing and dyeing, a synthetic resin dispersant, a coating film-forming agent, and a thickener. In the printing and dyeing industry, the original paste used for two-phase printing with vat dyes and reactive dyes requires the use of sodium hydroxide and caustic soda to reduce the vat dyes into a colorless substance before they can be dyed. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | FJ5959000 |
FLUKA BRAND F CODES | 3 |
TSCA | Yes |
HS Code | 39129000 |
Reference Show more | He Ye, Liu Guo-qin. Effect and mechanism analysis of edible coating on oil content and oil penetration of oil cake [J]. Modern Food Science and Technology, 2020, v.36;No.245(01):111 198-203. |
white powder or fiber, non-toxic. Tasteless. With excellent moisture retention, dispersion and stability. Methylcellulose is the product of the total and partial methylation of the three hydroxyl groups in the glucose that makes up cellulose. If all are methylated, the degree of substitution is 3 and the methoxy content is 45.6%. General products containing methoxy group is 26% ~ 33%, the degree of substitution of 1.7~2.2. The products with degree of substitution of 1.3~2.6 are soluble in water, pyridine and glacial acetic acid, and the products with degree of substitution of 2.4~2.8 are soluble in polar solvents. The nature of the product is related to the degree of substitution. At the same degree of substitution, the more uniform the distribution of the substituents, the lower the degree of polymerization, the better the solubility. When heated, its viscosity initially decreases with the increase of temperature, but when it reaches a certain temperature, it will become viscous and gel. Its powder and air can form an explosive mixture. Combustion explosion was caused by open flame and high heat energy.
The wood pulp or cotton pulp (cotton linter) and sodium hydroxide were mixed with water and soaked at about 30 °c. Then, the plate-like alkali cellulose was obtained by pressing. It is broken, so that the alkali cellulose tissue is loose and further homogenized, and the oxygen in the air is degraded, so that the degree of polymerization is reduced, in order to adjust the viscosity of the product. The reaction is then carried out by addition of an excess of methyl chloride, and the etherification is completed. Then the product is washed in hot water, then an appropriate amount of hydrochloric acid (or sulfuric acid) and oxalic acid are added to decolorize, washed to neutral, and dehydrated and dried to obtain a finished product.
This product is methyl ether cellulose. The methoxy group (-OCH3) should be 27.0% to 32.0% based on the dry product.
dispersant for polyvinyl chloride. In cosmetics, medicine, food industry, used as film-forming agent and adhesive, textile dyeing sizing agent, coating film-forming agent and thickener. Used in the construction industry as a mixture of cement, mortar, joint cement.
The product is irritating to the eyes and skin. Store in a cool, ventilated warehouse. Keep away from fire and heat source. Keep the container sealed. Prevent sun exposure. Should be stored separately from the oxidant.
for the test sample with the indicated viscosity lower than 600mPa • s, take 4.0g of this product (based on the dry product), add 196g of water at 90°C, and fully stir for about 10 minutes, cool in an ice bath, keep stirring for another 40 minutes during cooling, add cold water to a total weight of 200g, stir evenly, and adjust the temperature to 20°C ± 1°C, if necessary, the air bubbles in the solution can be removed by decompression method or centrifugation, and the flat viscometer suitable for the inner diameter of the capillary tube is selected for determination according to law (the first method of general rule 0633). The viscosity shall be 80% ~ 120% of the indicated viscosity; for label viscosity not less than 600MPa. s sample, take this product 10. Add 490g of water at 90 ° C., fully stir for about 10 minutes, cool in an ice bath, and keep stirring for another 40 minutes during cooling, add cold water to a total weight of 50 0G, stir well, and adjust the temperature to 20°C ± 0. 1°C, with NDJ-1 type viscometer, select the appropriate rotor and speed as shown in the following table, and measure according to law (General 0633 third method), the viscosity should be 75% ~ 140% of the indicated viscosity.
The solution under the item of viscosity was measured according to law (General rule 0631). The electrode immersion time was 5 minutes ± 0. 5 minutes, and the p H value should be 5. 0-8. 0.
take this product, dry at 105°C for 2 hours, loss of weight shall not exceed 5.0% (General rule 0831).
This product l.O g, inspection according to law (General 0841), residue shall not exceed 1.0%.
The residue left under the item of taking the ignition residue shall not contain more than 20 parts per million of heavy metal when examined by law (General rule 0821, Law II).
take this product l.O g, add calcium hydroxide l.O g, mix, add water and stir evenly, after drying, first burn with small fire to charring, then burn at 500~600°C to completely Ash and cool, add hydrochloric acid 8M l and water 23ML, according to the law inspection (General Principles 0822 The first law), should comply with the provisions (0.0002%).
methoxy take this product, precision weighing, according to the methoxy, ethoxy and hydroxypropoxy determination method (General 0712), that is obtained.
pharmaceutical excipients, adhesives and suspending agents.
sealed storage.
viscosity is indicated in units of mPa · s or Pa · s.