886762-08-9 - Names and Identifiers
886762-08-9 - Physico-chemical Properties
Molecular Formula | C7H5BrF3NO
|
Molar Mass | 256.02 |
Density | 1.726±0.06 g/cm3(Predicted) |
Boling Point | 230.2±35.0 °C(Predicted) |
Flash Point | 93°C |
Vapor Presure | 0.0666mmHg at 25°C |
pKa | 1.38±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.523 |
886762-08-9 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
UN IDs | UN2811 |
886762-08-9 - Introduction
5-Bromo-2-(trifluoromethoxy)aniline is an organic compound with the chemical formula C7H5BrF3NO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-Bromo-2-(trifluoromethoxy)aniline is a colorless to pale yellow solid.
-Solubility: It can be dissolved in some organic solvents, such as ethanol, dimethyl sulfoxide, etc.
-Melting point: Its melting point is about 58-62°C.
-Density: Its density is about 1.7g/cm³.
-Flammability: It is a combustible substance, and attention should be paid to avoid contact with open flames.
Use:
- 5-Bromo-2-(trifluoromethoxy)aniline is an important intermediate in organic synthesis. It can be used to synthesize compounds with a variety of biological activities, such as drugs, pesticides and dyes.
-For example, it can be used to synthesize new anti-cancer drugs, pesticides and organic light-emitting materials.
Preparation Method:
-A common preparation method is to react 2-amino-5-bromophenol with trifluoroformic acid and sodium nitrite to generate intermediate 2-trifluoromethoxy-5-bromophenol, which is then reduced to obtain 5-Bromo-2-(trifluoromethoxy)aniline.
-During the preparation process, care should be taken to avoid contact with toxic or irritating chemicals and reasonably control the reaction conditions.
Safety Information:
- 5-Bromo-2-(trifluoromethoxy)aniline should be stored in a dry, well-ventilated place, away from fire and high temperature.
-It is an irritant substance and may irritate the skin, eyes and respiratory tract. When using it, wear personal protective equipment such as protective glasses, gloves and protective masks.
-In the process of operation should follow the correct experimental procedures, avoid contact with the skin and inhalation of its vapor.
-After use, appropriate waste disposal methods should be adopted to avoid environmental pollution.
Last Update:2024-04-09 19:05:52