886363-18-4 - Names and Identifiers
886363-18-4 - Physico-chemical Properties
Molecular Formula | C15H11NO2
|
Molar Mass | 237.25 |
Density | 1.32g/cm3 |
Boling Point | 502.9°C at 760 mmHg |
Flash Point | 257.9°C |
Vapor Presure | 6.22E-11mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.707 |
886363-18-4 - Introduction
4-(1H-indol-5-yl)benzoic acid is an organic compound with the chemical formula C15H11NO2. It is a white crystalline powder with the smell of benzoic acid. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, methanol and dichloromethane
-Melting point: about 164-168°C
-Stability: stable at room temperature, but avoid contact with strong oxidants
- pH: Acidic
Use:
4-(1H-indol-5-yl)benzoic acid has many uses in chemical research and synthesis, including:
-As an intermediate of organic fluorescent materials, it can be used to synthesize fluorescent dyes and fluorescent probes containing indole groups
-for the synthesis of compounds with antibacterial, anti-tumor and other biological activities
-For the synthesis of indole-substituted pharmaceutical ingredients
Preparation Method:
One commonly used method of preparation is the synthesis of 4-(1H-indol-5-yl)benzoic acid by a synthetic reaction. A common synthetic route is:
1. benzoic acid and indole are heated and reacted under acidic conditions to generate 4-(1H-indol-5-yl)benzoic acid.
Safety Information:
- 4-(1H-indol-5-yl)benzoic acid is generally considered to have low toxicity. However, as an organic compound, it is still necessary to pay attention to safe operation and avoid contact with eyes, skin and inhalation. Wear appropriate personal protective equipment, such as lab gloves and protective glasses.
-Please seal the preservation, away from high temperature, fire and oxidant.
-When using and handling, please refer to the relevant safety data sheet (MSDS) to ensure safe operation.
Last Update:2024-04-09 02:00:48