[2-(tert-butoxycarbonylamino)pyrimidin-5-yl]boronic acid is an organic boron compound with the chemical formula C11H17BN4O3.
Nature:
[2-(tert-butoxycarbonylamino)pyrimidin-5-yl]boronic acid is a white crystalline solid with good solubility and is soluble in many organic solvents, such as dimethyl sulfoxide and dichloromethane. It has a medium molecular weight and a low melting point.
Use:
[2-(tert-butoxycarbonylamino)pyrimidin-5-yl]boronic acid is an important intermediate in organic synthesis. It can be used to synthesize drugs, pesticides, dyes and functional materials. In addition, since it contains a boronic acid group, it can also be used as a reagent for screening compounds and ligands.
Preparation Method:
A common preparation method is through the hydrolysis of [2-(tert-butoxycarbonylamino)pyrimidin-5-yl]boronic acid ester. First, the [2-(tert-butoxycarbonylamino)pyrimidin-5-yl]boronic acid ester is reacted with water or alcohol to give the corresponding [2-(tert-butoxycarbonylamino)pyrimidin-5-yl]boronic acid.
Safety Information:
[2-(tert-butoxycarbonylamino)pyrimidin-5-yl]boronic acid has relatively low toxicity under normal conditions of use. However, like all chemical substances, appropriate precautions are required when used. Avoid contact with skin and eyes, and make sure to use in a well-ventilated place. If exposed or inhaled, seek medical attention immediately.