874781-09-6 - Names and Identifiers
874781-09-6 - Physico-chemical Properties
Molecular Formula | C7H7F2NO3S
|
Molar Mass | 223.2 |
Density | 1.452g/cm3 |
Melting Point | 110.0 to 115.0 °C |
Boling Point | 344.8°C at 760 mmHg |
Flash Point | 162.3°C |
Vapor Presure | 6.42E-05mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.507 |
MDL | MFCD03407973 |
874781-09-6 - Introduction
4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE is a chemical substance with the chemical formula C7H6F2NO3S. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE is commonly a white crystalline solid.
-Melting point: about 135-137 degrees Celsius.
-Solubility: 4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE is soluble in many organic solvents, such as dimethyl sulfoxide and acetonitrile.
Use:
- 4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE is an important organic intermediate, commonly used in drug synthesis and pesticide manufacturing.
-In the pharmaceutical field, the compound can be used as a pharmaceutical raw material, such as an intermediate for the synthesis of anticancer drugs.
-In the manufacture of pesticides, 4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE can be used to synthesize compounds with insecticidal activity.
Preparation Method:
4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE has a variety of synthetic methods, common include the following:
-p-difluoromethoxybenzenesulfonyl chloride is obtained by reacting p-difluorotoluene with benzenesulfonyl chloride. The p-difluoromethoxybenzenesulfonyl chloride is then reacted with ammonia to produce 4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE.
-Through the reaction of p-difluorotoluene and benzenesulfonic acid, p-difluoromethoxybenzoic acid is generated, and then it is converted into 4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE through an acylation reaction.
Safety Information:
- 4-(DIFLUOROMETHOXY)BENZENESULFONAMIDE is less toxic, but should be handled with caution. Wear chemical protective goggles and gloves to avoid contact with skin and inhalation of dust.
-When storing and handling, keep away from fire and oxidant to avoid fire or explosion accidents.
-If taken by mistake or inhaled, seek medical attention immediately. If eye or skin contact occurs, rinse with water for at least 15 minutes and seek medical help.
Please note that this information is for informational purposes only and detailed nature, use, manufacturing and safety information should be understood and followed in detail in the specific application.
Last Update:2024-04-09 15:18:00