870779-01-4 - Names and Identifiers
870779-01-4 - Physico-chemical Properties
Molecular Formula | C13H12BFO3
|
Molar Mass | 246.04 |
Density | 1.26g/cm3 |
Melting Point | 94-106°C(lit.) |
Boling Point | 432.9°C at 760 mmHg |
Flash Point | 215.6°C |
Vapor Presure | 2.92E-08mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.577 |
870779-01-4 - Risk and Safety
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
870779-01-4 - Introduction
{2-[(4-fluorobenzyl)oxy]phenyl}boronic acid is an organic compound with the chemical formula C13H11BFO3.
Its properties are as follows:
Appearance: White solid
Molecular weight: 244.03g/mol
Melting point: about 160-162°C
Boiling point: about 416-419°C
Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide.
{2-[(4-fluorobenzyl)oxy]phenyl}boronic acid is mainly used for metal-catalyzed reactions in organic synthesis. It is an important boron reagent and can be used as an introduction group of aromatic compounds. It can participate in cross-coupling reactions of phenyl groups, such as Suzuki coupling reactions, to form new chemical bonds. In addition, it can also be used in the construction of organic electronic materials, drug synthesis and other fields.
A common method for preparing {2-[(4-fluorobenzyl)oxy]phenyl}boronic acid is diazotization of 4-fluorobenzyl alcohol and phenylboronic acid in the presence of alkali, and then conversion to the target product through an acidic process.
About safety information,{2-[(4-fluorobenzyl)oxy]phenyl}boronic acid is a general organic compound. Generally, the following safety measures should be paid attention to during operation:
-Avoid inhaling its dust or gas, and wear a suitable protective mask if necessary.
-Avoid contact with the skin, such as the need to operate should wear appropriate protective gloves and lab coat.
-avoid eating or intake, such as eating should be timely medical treatment.
-Maintain good ventilation during operation, and properly store and handle the compound in the laboratory.
Last Update:2024-04-09 20:02:46