Boc-N-Me-D-Phe-OH(Boc-N-Me-D-Phe-OH) is an organic compound with the following properties:
1. Appearance: White crystalline solid.
2. Solubility: Soluble in organic solvents such as methanol, ethanol and dichloromethane, and slightly soluble in water.
3. Chemical properties: Boc-N-Me-D-Phe-OH is an amide compound with a stable acyl protecting group (N-tert-butoxycarbonyl-Boc). It can remove the Boc protecting group by hydrolysis, exposing the amine group, thus participating in other organic synthesis reactions.
The main uses of the Boc-N-Me-D-Phe-OH are as follows:
1. protecting groups in organic synthesis: as one of the acyl protecting groups, amino groups in natural amino acids or synthetic peptides can be protected to prevent them from being changed by intention in the reaction.
2. Starting materials in peptide synthesis: can be used to synthesize polypeptides, especially peptides with specific sequences and structures.
Boc-N-Me-D-Phe-OH preparation method generally has two kinds of commonly used methods:
1. Synthesis by acylation reaction: The amine group of D-phenylalanine was acylated with tert-butoxycarbonyl acid (Boc-NH2) to obtain Boc-N-Me-D-Phe-OH.
2. synthesis by peptide synthesis reaction: the Boc-N-Me-D-Phe-OH and other peptide raw materials are connected by peptide synthesis reaction and subsequent processing, and finally the target polypeptide is obtained.
Regarding safety information, Boc-N-Me-D-Phe-OH is generally relatively safe under normal conditions, but as a chemical, the following matters still need to be paid attention:
1. avoid direct contact with skin and eyes, use should wear personal protective equipment, such as gloves and goggles.
2. Avoid inhaling its dust or vapor during operation, storage or disposal.
3. storage requirements: to be stored in a dry, dark environment, and keep sealed.
4. Follow proper laboratory procedures and safety practices.
When using or handling the compound, it is best to refer to the safety data form provided by the supplier or consult a professional for more detailed and accurate safety information.