N-(4-Oxobutyl)carbamic acid tert-butyl ester is an organic compound with the chemical formula C9H17NO3.
Nature:
1. Appearance: N-(4-Oxobutyl)carbamic acid tert-butyl ester is a colorless liquid or crystalline solid.
2. Solubility: It has good solubility and is soluble in organic solvents such as ethanol, acetone and dimethylformamide.
Use:
1. N-(4-Oxobutyl)carbamic acid tert-butyl ester is an important organic synthesis intermediate, which is widely used in the preparation of drugs, pesticides and chemical reagents.
2. It can also be applied to the synthesis of enzyme inhibitors with high catalytic activity.
Preparation Method:
N-(4-Oxobutyl)carbamic acid tert-butyl ester can usually be synthesized through the following steps:
1. firstly, 4-aminobutyraldehyde reacts with di-tert-butyl carbodiate to generate tert-butyl N-(4-aminobutyl) carbamate.
2. Then, for example, the intermediate is oxidized to N-(4-Oxobutyl)carbamic acid tert-butyl ester through an oxidation reaction.
Safety Information:
Specific toxicity data for N-(4-Oxobutyl)carbamic acid tert-butyl ester may be difficult to obtain, so it is necessary to follow routine laboratory safety procedures when using this compound, including wearing protective glasses and gloves, and ensuring that the operation is carried out under well-ventilated conditions. In addition, care must be taken to avoid contact with the skin, eyes and respiratory tract.