845829-94-9 - Names and Identifiers
845829-94-9 - Physico-chemical Properties
Molecular Formula | C7H6BrFO
|
Molar Mass | 205.02 |
Density | 1.531±0.06 g/cm3(Predicted) |
Boling Point | 208.6±20.0 °C(Predicted) |
Flash Point | 94.4°C |
Vapor Presure | 0.306mmHg at 25°C |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.518 |
845829-94-9 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
845829-94-9 - Introduction
2-Bromo-6-fluoroanisole, chemical formula C7H6BrFO, is an organic compound. The following is its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Bromo-6-fluoroanisole is a colorless to pale yellow liquid.
-Melting point: about -20 ℃.
-Boiling point: about 211 ℃.
-Density: about 1.665g/cm3.
-Solubility: It is soluble in some organic solvents, such as ethanol, toluene, etc., but insoluble in water.
Use:
2-Bromo-6-fluoroanisole is widely used in the field of organic synthesis and is often used as an intermediate or reagent in organic synthesis, such:
-It can be used as a drug synthesis intermediate, in the pharmaceutical industry for the synthesis of anti-cancer drugs, antibiotics, etc.
-It can also be used as a fluorination reagent or bromination reagent in organic synthesis reactions.
Preparation Method:
2-Bromo-6-fluoroanisole can be prepared by the following methods, one of which is the fluorination reaction of brominated anisole. The specific steps are as follows:
1. Synthesis of brominated anisole, that is, bromine reacts with anisole to generate 2-bromoanisole.
2. 2-bromoanisole reacts with fluorine gas to generate 2-Bromo-6-fluoroanisole.
Safety Information:
- 2-Bromo-6-fluoroanisole should be properly stored away from fire sources, heat sources and oxidants, and avoid contact with flames or high temperatures.
-Wear appropriate personal protective equipment such as safety glasses, gloves and protective clothing during operation.
-When in use, provide good ventilation conditions to avoid inhalation or contact with skin.
-In case of inhalation or accidental contact, rinse immediately and seek medical help.
-Follow local safety practices during handling and disposal.
Last Update:2024-04-09 15:18:00