83621-33-4 - Names and Identifiers
83621-33-4 - Physico-chemical Properties
Molecular Formula | C14H17NO3
|
Molar Mass | 247.29 |
Density | 1.177±0.06 g/cm3(Predicted) |
Boling Point | 398.2±42.0 °C(Predicted) |
Flash Point | 194.612°C |
Vapor Presure | 0mmHg at 25°C |
pKa | -1.55±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.549 |
83621-33-4 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 52 - Harmful to aquatic organisms
|
WGK Germany | 3 |
Hazard Note | Irritant |
83621-33-4 - Introduction
N-Cbz-hexahydro-1H-azepin-4-one(N-Cbz-hexahydro-1H-azepin-4-one), also known simply as Cbz-azepinone, is an organic compound.
Nature:
N-Cbz-hexahydro-1H-azepin-4-one is a colorless to slightly yellow liquid or solid. It has a special molecular structure, including a ring structure containing 6 carbon atoms and an oxoazepine group. It has good chemical stability and can be dissolved in organic solvents under certain conditions.
Use:
N-Cbz-hexahydro-1H-azepin-4-one are often used as substrates or intermediates in organic synthesis. It can be used as a starting material for the synthesis of other compounds, such as bioactive molecules, drug molecules and heterocyclic compounds. It can also be used as a precursor for the synthesis of heterocyclic compounds.
Preparation Method:
There are many preparation methods of N-Cbz-hexahydro-1H-azepin-4-one. The commonly used method is to synthesize by condensation reaction with amino acid benzyl ester. The reaction is carried out under basic conditions, and the inlet material is the substrate amino acid benzyl ester and an alkali metal catalyst such as NaH. In addition, the N-Cbz-hexahydro-1H-azepin-4-one can also be synthesized by other methods, such as hydrogenation reaction, ring-closing reaction, etc.
Safety Information:
The N-Cbz-hexahydro-1H-azepin-4-one is relatively stable under general conditions, but it is still necessary to pay attention to the safety of operation. Because it is an organic compound, it is irritating and possibly toxic. Wear appropriate protective gloves and glasses to avoid direct contact with skin and eyes. In addition, avoid mixing with oxidants and strong acids, strong bases and other chemicals during operation or storage to avoid accidental reactions. If skin or eye contact occurs, rinse immediately with plenty of water and seek medical help. During use and storage, the relevant chemical safety practices should be followed.
Last Update:2024-04-09 21:04:16