Name | concanamycin A from streptomyces species |
Synonyms | S-45A A661-I CONCANAMYCIN A Antibiotic A661I Antibiotic S-45A CONCANAMYCIN A, STREPTOMYCES SP concanamycin A from streptomyces species (3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyloxacyclooctadeca-3,5,13,15-tetraen-2-one |
CAS | 80890-47-7 |
EINECS | 620-709-4 |
InChI | InChI=1/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22-23H2,1-12H3,(H2,47,53)/b16-13+,18-15+,24-17+,25-20+,36-21-/t26-,27-,28-,29+,30+,31-,32+,33-,34-,35+,37-,38+,39+,40-,41-,42-,43-,46-/m1/s1 |
Molecular Formula | C46H75NO14 |
Molar Mass | 866.09 |
Density | 1.20±0.1 g/cm3(Predicted) |
Melting Point | 179-180℃ (dichloromethane ethanol ) |
Boling Point | 966.4±65.0 °C(Predicted) |
Flash Point | 538.3°C |
Solubility | Soluble in DMSO |
Vapor Presure | 0mmHg at 25°C |
Appearance | Lyophilized solid |
Color | White |
BRN | 3560277 |
pKa | 12.46±0.70(Predicted) |
Storage Condition | −20°C |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
Refractive Index | 1.554 |
MDL | MFCD00210037 |
Hazard Symbols | T+ - Very toxic |
Risk Codes | R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. R36 - Irritating to the eyes |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 3462 6.1/PG 2 |
WGK Germany | 3 |
RTECS | CB9732000 |
FLUKA BRAND F CODES | 10-21 |
Hazard Class | 6.1(b) |
Packing Group | III |
biological activity | , it is also a specific vacuolar H-ATP enzyme (V-ATPase) inhibitor.|
Target | vacuum type H -ATPase |