Molecular Formula | C8H9N3O5S |
Molar Mass | 259.24 |
Density | 1?+-.0.1 g/cm3(Predicted) |
Melting Point | >160°C (dec.) |
Boling Point | 481.1±51.0 °C(Predicted) |
Flash Point | 244.74°C |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
pKa | 2.40±0.10(Predicted) |
Storage Condition | Refrigerator, under inert atmosphere |
Refractive Index | 1.655 |
Physical and Chemical Properties | Appearance: Almost white or light yellow crystalline powder |
Use | Used as an intermediate in organic synthesis |
Use | (Z)-2-(2-amino-4-thiazolyl)-2-methoxycarbonylmethoxyiminoacetic acid (cefixime side chain acid) is an important side chain intermediate for the synthesis of the 3rd and 4th generation cephalosporins, it is of great economic and practical value to strengthen its research and development. used as intermediate in organic synthesis |
preparation | the synthesis of cefixime side chain acid is based on tert-butyl acetoacetate as raw material, after oximation, etherification, chlorination, (Z)-2-(2-aminothiazol-4-yl)-2-methoxycarbonylmethoxyiminoacetic acid was synthesized in the steps of cyclization and hydrolysis. |