Name | P-(N,N-dichlorosulfamyl)benzoic acid |
Synonyms | Halazone HALAZONE 4-dichlorosulphamoylbenzoic acid p-Sulfondichloraminobenzoic acid 4-(DICHLOROSULFAMOYL)BENZOIC ACID 4-(Dichlorosulfamoyl)benzoic Acid P-(N,N-dichlorosulfamyl)benzoic acid PARA-SULPHONEDICHLORAMIDOBENZOICACID 4-(N,N-Dichlorosulfamoyl)benzoic acid |
CAS | 80-13-7 |
EINECS | 201-253-1 |
InChI | InChI=1/C7H5Cl2NO4S/c8-10(9)15(13,14)6-3-1-5(2-4-6)7(11)12/h1-4H,(H,11,12) |
Molecular Formula | C7H5Cl2NO4S |
Molar Mass | 270.09 |
Density | 1.5426 (rough estimate) |
Melting Point | 195°C (rough estimate) |
Boling Point | 437.0±47.0 °C(Predicted) |
Appearance | neat |
Merck | 14,4590 |
pKa | 3.29±0.10(Predicted) |
Storage Condition | 2-8℃ |
Stability | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
Refractive Index | 1.6000 (estimate) |
MDL | MFCD00045858 |
Physical and Chemical Properties | White Crystal or crystalline powder. Decomposition at about 195 °c. Slightly soluble in water and chloroform, soluble in alkaline solution. Chlorine odor. |
In vitro study | Halazone is chemically closely related to Chloramine-T, the nitrogen atom is linked with two instead of one chlorine atom and, certainly more important here, a methyl group is replaced by a carboxyl group. The effect of Halazone on the sodium current is studied in voltage-clamped single nerve fibers of the frog. The oxidant Halazone drastically inhibits inactivation. |
UN IDs | 1479 |
WGK Germany | 3 |
RTECS | DG8050000 |
Hazard Class | 5.1 |
Packing Group | III |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
biological activity | Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used for drinking water Disinfection. |
purpose | This product is Disinfection preservative, Disinfection for drinking water. |
production method | from sodium p-aminosulfonyl benzoate by chlorination. A 25% solution of sodium p-aminosulfonyl benzoate was prepared by dissolving p-aminosulfonyl benzoic acid in sodium hydroxide solution. This solution was placed in a chlorination Pan and sodium hydroxide solution was added. Chlorine gas is introduced below 5 ℃, and the end point of the reaction solution test is taken when the temperature reaches pH7-8 (the end point is acid addition after the reaction solution is filtered and no precipitate is added). After reaching the end point, the passage of chlorine was stopped, stirred for 15min, and filtered. The filter cake was washed with water, spin dried and dried at below 40 °c. Halazone was crushed and screened. The yield was 85%. |
category | pesticide |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD50 3500 mg/kg; Intravenous-rat LD50: 300 mg/kg |
flammability hazard characteristics | flammable, fire discharge NOx, sulfur oxides and chlorides spicy irritant smoke |
storage and transportation characteristics | warehouse low temperature, ventilation, dry |
extinguishing agent | water, carbon dioxide, dry powder, sand |