797804-50-3 - Names and Identifiers
797804-50-3 - Physico-chemical Properties
Molecular Formula | C10H8N2O3
|
Molar Mass | 204.18 |
Storage Condition | 2-8℃ |
797804-50-3 - Introduction
1H-Indazole-5-carboxylic acid, 3-formyl-, methyl ester is an organic compound with the chemical formula C10H8N2O3.
Properties of the compound include:
-Appearance: Colorless or light yellow solid
-Melting point: about 150-152°C
-Boiling point: about 376°C
-Solubility: Soluble in most organic solvents, such as ethanol, dimethylformamide and dichloromethane, insoluble in water.
One of the main uses of 1H-Indazole-5-carboxylic acid, 3-formyl-, methyl ester is as a pharmaceutical intermediate. It can be used to synthesize a variety of bioactive indazole compounds, such as anti-tumor drugs, anti-inflammatory drugs and antibacterial drugs. In addition, it can also be used for other synthetic reactions in the field of organic synthesis.
1H-Indazole-5-carboxylic acid, 3-formyl-, methyl ester can be prepared by the following steps:
1. First, 3-pyridinecarboxylic acid and formaldehyde are reacted to generate 3-aldehyde pyridine.
2. Next, the obtained 3-aldehyde pyridine is reacted with methyl cyanate to produce methyl 3-aldehyde picolinate.
3. finally, methyl 3-aldehyde picolinate is reacted with ammonia or ammonia solution to generate 1H-Indazole-5-carboxylic acid, 3-formyl-, methyl ester.
For safety information, 1H-Indazole-5-carboxylic acid, 3-formyl-, methyl ester should follow laboratory safety procedures. This is an organic chemical reagent that can be dangerous. Contact with skin, eyes and respiratory tract should be avoided during handling. Operations should be carried out in a well-ventilated area and appropriate personal protective equipment, such as lab gloves and goggles, should be worn. If inhaled or in contact with skin, rinse immediately with water and seek medical help.
Last Update:2024-04-09 21:01:54