Name | 2-Methyl-1-propanol |
Synonyms | IBA FEMA 2179 ISOBUTANOL Isobutanol Iso-Butanol Iso Butanol Isobutyl alcohol ISOBUTYL ALCOHOL ISOPROPYL CARBINOL 2-Methyl-1-propanol ISO-PROPYL BARBINOL Natural Isobutyl Alcohol NATURAL ISO BUTYL ALCOHOL ISOBUTANOL, 2-METHYL-1-PROPANOL |
CAS | 78-83-1 |
EINECS | 201-148-0 |
InChI | InChI=1/C4H10O/c1-4(2)3-5/h4-5H,3H2,1-2H3 |
InChIKey | ZXEKIIBDNHEJCQ-UHFFFAOYSA-N |
Molecular Formula | C4H10O |
Molar Mass | 74.12 |
Density | 0.803 g/mL at 25 °C (lit.) |
Melting Point | -108 °C (lit.) |
Boling Point | 108 °C (lit.)108 °C |
Flash Point | 82°F |
JECFA Number | 251 |
Water Solubility | 95 g/L (20 ºC) |
Solubility | water: miscible70g/L at 20°C |
Vapor Presure | 8 mm Hg ( 20 °C) |
Vapor Density | 2.55 (vs air) |
Appearance | Solid |
Color | APHA: ≤10 |
Odor | Slightly suffocating; nonresidual alcoholi |
Exposure Limit | TWA 300 mg/m3 (100 ppm) NIOSH, 150mg/m3 (50 ppm) (ACGIH); IDLH 8000 ppm. |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.10', , 'λ: 280 nm Amax: 0.06'] |
Merck | 14,5131 |
BRN | 1730878 |
pKa | >14 (Schwarzenbach et al., 1993) |
PH | 7 (80g/l, H2O, 20℃) |
Storage Condition | Store at +5°C to +30°C. |
Stability | Stable. Flammable. Incompatible with strong oxidizing agents, aluminium. |
Explosive Limit | 1.5-12%(V) |
Refractive Index | n20/D 1.396(lit.) |
Physical and Chemical Properties | Character: colorless transparent liquid. Special odor. melting point -108 ℃ boiling point 108.1 ℃ relative density 0.806 refractive index 1.3976 flash point 27.5 ℃ soluble in about 20 times of water, miscible with ethanol and ether. |
Use | Used as a raw material for organic synthesis, also used as an advanced solvent |
Hazard Symbols | Xi - Irritant |
Risk Codes | R10 - Flammable R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R67 - Vapors may cause drowsiness and dizziness |
Safety Description | S13 - Keep away from food, drink and animal foodstuffs. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S46 - If swallowed, seek medical advice immediately and show this container or label. S7/9 - |
UN IDs | UN 1212 3/PG 3 |
WGK Germany | 1 |
RTECS | NP9625000 |
TSCA | Yes |
HS Code | 29051990 |
Hazard Class | 3 |
Packing Group | III |
Toxicity | LD50 orally in rats: 2.46 g/kg (Smyth) |
colorless transparent liquid with special odor. Miscible with ethanol and ether, soluble in about 20 parts of water. Flammable, its vapor and air can form an explosive mixture, in the case of open flame, high heat energy caused by combustion explosion. Toxic gases are released by thermal decomposition. A strong reaction with an oxidizing agent can occur.
with propylene and synthesis gas as raw materials, through the carbonyl synthesis, the normal and isobutyraldehyde were obtained, after the catalyst was removed, the product was hydrogenated to normal and isobutanol, and the product was obtained by dehydration and separation, respectively. Alternatively, isobutyraldehyde is subjected to liquid phase hydrogenation reaction under the catalysis of nickel to obtain isobutanol. It can also be recovered from isobutyl oil, which is a by-product of a methanol plant. Isobutyl oil is demethanized, salted out and dehydrated, and then subjected to azeotropic distillation to obtain isobutanol.
reagents for the determination of calcium, strontium, barium, sodium, potassium, lithium, silver, chloride and phosphite. Chromatographic analysis of reference substances. It is also a common solvent and extractant. For the extraction of lithium chloride from a mixture of lithium chloride and sodium chloride or potassium chloride. Used in the manufacture of petroleum additives, antioxidants, 2,6-= tert-butyl-p-cresol, isobutyl acetate (coating solvent), plasticizers, synthetic rubber, artificial musk; Fruit essential oil and synthetic drugs.
rat oral LD50: 2460 mg/kg; Rabbit percutaneous LDso: 3400 mg/kg. Higher concentrations of vapor are irritating to the eyes, skin, mucous membranes and upper respiratory tract. Store in a cool, ventilated warehouse. Keep away from fire and heat source. Storage temperature should not exceed 30 ℃. Keep the container sealed. It should be stored separately from oxidants and acids, and mixed storage should not be avoided.