Name | Tributyl citrate(TBC) |
Synonyms | Citroflex 4 N-BUTYLCITRATE TRIBUTYL CITRATE Tributyl citrate TRI-N-BUTYL CITRATE Tributyl citrate(TBC) TRIPHENYLBENZYLPHOSPHONIUM CHLORIDE tributyl 2-hydroxypropane-1,2,3-tricarboxylate 2,3-propanetricarboxylicacid,2-hydroxy-tributylester 1,2,3-Propanetricarboxylicacid,2-hydroxy-,tributylester 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tributyl ester |
CAS | 77-94-1 |
EINECS | 201-071-2 |
InChI | InChI=1/C18H32O7/c1-4-7-10-23-15(19)13-18(22,17(21)25-12-9-6-3)14-16(20)24-11-8-5-2/h22H,4-14H2,1-3H3 |
InChIKey | ZFOZVQLOBQUTQQ-UHFFFAOYSA-N |
Molecular Formula | C18H32O7 |
Molar Mass | 360.44 |
Density | 1.043 g/mL at 20 °C (lit.) |
Melting Point | ≥300°C(lit.) |
Boling Point | 234 °C (17 mmHg) |
Flash Point | 300 °C |
Water Solubility | insoluble |
Solubility | Miscible with acetone, ethanol, and vegetable oil;practically insoluble in water. |
Vapor Presure | 1.09E-07mmHg at 25°C |
Appearance | Liquid |
Color | Clear |
Merck | 14,1564 |
BRN | 1806072 |
pKa | 11.30±0.29(Predicted) |
Storage Condition | Store below +30°C. |
Refractive Index | n20/D 1.445 |
Physical and Chemical Properties | Colorless oily liquid, slightly odorous. melting point -20 ℃ boiling point 233 ℃ relative density 1.045 refractive index 1.4460 flash point 185 ℃ solubility insoluble in water, soluble in methanol, acetone, carbon tetrachloride, acetic acid, castor oil, mineral oil and other organic solvents. |
Use | Mainly used as plasticizers for vinyl resins and cellulose resins |
Hazard Symbols | T - Toxic |
Risk Codes | 25 - Toxic if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. |
UN IDs | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | TZ8608000 |
TSCA | Yes |
HS Code | 29181500 |
This product is 2-hydroxypropane-1, 2, 3-tricarboxylic acid tri-n-butyl ester. It is prepared by esterification of citric acid and n-butanol under the action of catalyst, and then refined by de-esterification, neutralization and water washing. Calculated as anhydrous, containing no less than 99.0% of C18H320 7.
The relative density of this product (General 0601) at 25°C is 1. 037~1.045 0
The refractive index of this product (General 0622) is 1. 443~1.445 at 25°C.
take this product 16. 0g, add 16ml of neutral ethanol to the indicator solution of bromothymol blue, mix well, immediately add the indicator solution of bromothymol blue (0. 1% ethanol solution) several drops, with sodium hydroxide titration solution (0, lm o l/L) titration solution to blue, consumption of sodium hydroxide titration solution (O .lm o l/L) the volume must not exceed Q. 5ml.
take this product, add dichloromethane to dissolve and dilute to make a solution containing 30mg per lml as a test solution; Take 1ml for precision measurement and put it in a 100ml measuring flask, dichloromethane was added to dilute to the scale, shake, as a control solution. According to the chromatographic conditions under the content determination item, if there are impurity peaks in the chromatogram of the test solution, the area of a single impurity peak shall not be greater than 0 .5 times (0 .5% ), the sum of each impurity peak area shall not be greater than 1 .5 times (1 .5%).
take an appropriate amount of this product, according to the determination method of moisture (General rule 0832 first method 1), the water content shall not exceed 0 .2%.
take the product l .O g, check according to law (General rule 0841), residue should not pass 0. 1%.
The residue left under the item of taking the ignition residue shall be inspected according to law (General Principles 0821 second law) and shall not contain more than 10 parts per million of heavy metals.
take this product 0.67g, add calcium hydroxide l.O g, mix, add water and stir evenly, after drying, first burn with a small fire to make charring, then burn at 500~600°C to make it ash completely, and let it cool, add hydrochloric acid 5M l and water 23ml to dissolve, check according to law (General Principles 0822 The first law), should comply with the provisions (0.0003%).
measured by gas chromatography (General 0521).
pharmaceutical excipients, plasticizers.
sealed storage.