75416-50-1 - Names and Identifiers
Name | 8-chloro-1,2,3,4-tetrahydroisoquinoline
|
Synonyms | C90103 8-Chloro-1,2,3,4-tetrahydroisoquinoline 8-chloro-1,2,3,4-tetrahydroisoquinoline Isoquinoline, 8-chloro-1,2,3,4-tetrahydro-
|
CAS | 75416-50-1
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EINECS | 821-607-4 |
InChI | InChI=1S/C9H10ClN/c10-9-3-1-2-7-4-5-11-6-8(7)9/h1-3,11H,4-6H2 |
75416-50-1 - Physico-chemical Properties
Molecular Formula | C9H10ClN
|
Molar Mass | 167.64 |
Density | 1.162±0.06 g/cm3(Predicted) |
Boling Point | 276.5±40.0 °C(Predicted) |
pKa | 8.75±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
75416-50-1 - Introduction
8-choro-1, 2,3,4-tetrahydroisoquinoline (8-choro-1, 2,3,4-tetrahydroisoquinoline) is an organic compound with the molecular formula C9H10ClN and the structural formula is as follows:
CH3-CH2-CH2-CH2-CH2-CH(Cl)-CH2-N
The following is a description of its nature, use, method and safety information:
Nature:
8-cholo-1, 2,3,4-tetrahydroisoquinoline is a colorless to pale yellow liquid with a peculiar aromatic odor. It is soluble in alcohol and ether at room temperature, slightly soluble in water. It has certain toxicity and irritation.
Use:
8-cholo-1, 2,3,4-tetrahydroisoquinoline is commonly used as an intermediate or starting material in organic synthesis. It can be used to synthesize drugs, dyes and chemical reagents containing quinoline nucleus.
Preparation Method:
there are many preparation methods of 8-chloro-1,2,3,4-tetrahydroisoquinoline. the common method is to react benzene or benzoic acid with ethanolamine to generate ethanolamine hydrochloride, and then react with chlorinated oxalylmethane to generate 8-chloro-1,2,3,4-tetrahydroisoquinoline.
Safety Information:
8-chloro-1,2,3,4-tetrahydroisoquinoline is irritating to the eyes, skin and respiratory tract and should be avoided. During the operation, ventilation should be strengthened and appropriate protective equipment should be worn. In case of accidental contact or inhalation, rinse immediately with water or seek medical help. During storage and handling, care should be taken to avoid contact with oxidants and strong acids to prevent fire.
Last Update:2024-04-09 15:17:59