73852-18-3 - Names and Identifiers
Name | 2,4,6-Trichlorophenylboronic acid
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Synonyms | RARECHEM AH PB 0058 2,4,6-Trichlorophenylboronicaci 2,4,6-Trichlorophenylboronic acid 2,4,6-TRICHLOROPHENYLBORONIC ACID 2,4,6-Trichlorobenzeneboronic acid 2,4,6-TRICHLOROBENZENEBORONIC ACID Boronic acid, B-(2,4,6-trichlorophenyl)- Boronic acid,(2,4,6-trichlorophenyl)- (9CI) 2,4,6-Trichlorobenzeneboronic acid(contains varying amounts of Anhydride) 2,4,6-Trichlorophenylboronic Acid (contains varying amounts of Anhydride)
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CAS | 73852-18-3
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InChI | InChI=1/C6H4BCl3O2/c8-3-1-4(9)6(7(11)12)5(10)2-3/h1-2,11-12H |
73852-18-3 - Physico-chemical Properties
Molecular Formula | C6H4BCl3O2
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Molar Mass | 225.26 |
Density | 1.60±0.1 g/cm3(Predicted) |
Melting Point | 162-164 |
Boling Point | 363.9±52.0 °C(Predicted) |
Flash Point | 173.9°C |
Solubility | soluble in Methanol |
Vapor Presure | 6.22E-06mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
pKa | 7.80±0.58(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.594 |
MDL | MFCD01074621 |
73852-18-3 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Hazard Note | Harmful/Irritant/Keep Cold |
73852-18-3 - Introduction
2,4, 6-Trichorylboronic acid is an organic compound with the chemical formula C6H3Cl3BO2. It is a white crystalline solid, hygroscopic at room temperature. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 251.33g/mol
-melting point: 179-182 ℃
-Solubility: High solubility in non-polar solvents (such as ether), difficult to dissolve in water
-Stability: relatively stable at room temperature, but may decompose under high temperature, high humidity or light conditions
Use:
2,4,6-Trichlorophenylboronic acid is mainly used in organic synthesis reactions, especially as an important derivative of ligands in metal ligand catalyzed reactions. It can be used as a precursor of tertiary amine ligands, and palladium and other metal coordination to form a stable complex, used in C- C bond formation reaction, reduction reaction and C- H bond functionalization reaction. In addition, it can also be used to prepare pharmaceutical intermediates, photoelectric materials, etc.
Preparation Method:
The preparation method of 2,4,6-Trichlorophenylboronic acid is generally obtained by reacting 2,4, 6-trichlorophenylboronic compound with acid. Common synthetic methods include the reaction of boric acid with 2,4, 6-trichlorophenylmagnesium solution, or the hydrolysis of 2,4, 6-Tricholophenylboronic acid ester to obtain the target product.
Safety Information:
- 2,4, 6-Trichorophenylboronic acid is an organic compound and should comply with general laboratory safety practices.
-Wear appropriate personal protective equipment, such as lab gloves, glasses, and lab coats.
-Avoid direct contact with skin, eyes and respiratory tract.
-Use should be operated in a well-ventilated place to avoid inhaling its steam or dust.
-in storage, should be sealed in a cool, dry place, away from heat and fire.
-Detailed toxicological data and safety information can be obtained from chemical suppliers or relevant databases. When using or handling this compound, please follow the relevant safety guidelines and regulations.
Last Update:2024-04-09 02:00:47