Molecular Formula | C21H38BrN |
Molar Mass | 384.44 |
Melting Point | 50-55°C |
Flash Point | 110°C |
Solubility | H2O: soluble0.1g/10 mL, clear, colorless to very faintly yellow |
Appearance | Solid |
Color | Crystals |
BRN | 3579193 |
Storage Condition | 2-8°C |
MDL | MFCD00011768 |
Physical and Chemical Properties | Appearance: yellow colloidal body at room temperature, stable, non-irritating |
Use | As a Disinfection preservative in medicine, it is used for Hand Sanitization before surgery, Disinfection for skin and Disinfection for medical devices, and as a biocide and algicide in industrial water treatment. |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | BO7875000 |
HS Code | 29239000 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | LD50 orl-rat: 250 mg/kg RPZHAW 17,543,66 |
Reference Show more | 1. Wang, Fangyuan, et al. "Facile nose-to-brain delivery of rotigotine-loaded polymer micelles thermosensitive hydrogels: In vitro characterization and in vivo behavior study." International journal of pharmaceutics 577 (2020): 119046.https://doi.org/10.1016/ 2. [IF=5.875] Fangyuan Wang et al."Facile nose-to-brain delivery of rotigotine-loaded polymer micelles thermosensitive hydrogels: In vitro characterization and in vivo behavior study."Int J Pharmaceut. 2020 Mar;577:119046 |
colorless or pale yellow solid or colloidal liquid. There is aromatic gas, bitter taste. There are typical cationic surfactant properties, soluble in water or ethanol. Stable nature, light-resistant, heat-resistant, non-volatile. There is a good dispersion, stripping sticky mud role.
dodecyl dimethyl benzyl ammonium bromide was obtained from decanediol by bromination reaction and then reacted with N.N-= methyl phenyl tertiary amine.
pharmaceutical excipients, bacteriostatic agents.
This product is a mixture of dimethyl benzyl ammonium bromide. The hydrocarbon-containing ammonium salt (C22H40BrN) should be between 95.0% and 105.0%, calculated as anhydrous.
Non-oxidative biocide, slime stripper and cleaner. With a clean, bactericidal Disinfection and anti-algae effect, widely used in sterilization, Disinfection, anti-corrosion, emulsification, descaling, solubilization and so on. Its bactericidal activity is better than that of benzalkonium chloride, and its toxicity is lower than that of benzalkonium chloride. In general, it is used at a concentration of 50 to 100mg/L.
small toxicity, no cumulative toxicity, skin irritation, LD50 to fish 15mg/L. Should be sealed and protected from light.
take this product l. Add 100ml of exothermic water to dissolve, and the solution should be clear and colorless; If it is turbid, it should not be more concentrated compared with No. 1 turbidity standard solution (General rule 0902 method 1); If it is colored, comparison with yellow No. 2 Standard Colorimetric solution (General rule 0901 first method), not deeper.
take this product solution (2-100)5ml, put the test tube, add sodium hydroxide solution 3ml, heat boiling, ammonia odor should not occur.
take 4.0g of this product, add water to dissolve and dilute to 100ml, take 25.0ML, set up a separatory funnel, add 25ml of chloroform and sodium hydroxide titration solution (0.1 mol/L) 10ml, Add 10ml of new 5% potassium iodide solution, shake, stand still to make layers, separate the water layer and wash with chloroform shaking for 3 times, 10ml each time, discard the chloroform layer, add hydrochloric acid 40ml to the water layer, cool down, add 50% potassium bromide solution 40ml, Titrate to light brown with potassium iodate titration solution (0.05mol/L), add chloroform 2ml, continue titration and shake vigorously until the red color of the chloroform layer disappears; Take another 25.0 of the remaining aqueous solution and put it in a separatory funnel. Add 25ml of chloroform and hydrochloric acid titration solution (0.1 mol/L) 10ml, according to the above method, from the "precision of the new 5% potassium iodide solution 10ml", according to the law. Before and after the two consumption of potassium gallate titration solution (0.05mol/L), the difference should not be greater than 0.5.
take this product, according to the determination of moisture (General 0832 first method 1), the water content shall not exceed 10.0%.
take l.Og of this product and check it according to law (General rule 0841). The residue left shall not exceed 0.1%.
take about 0.25g of this product, accurately weigh it, put it in a plug Erlenmeyer flask, add 50ml of water and 1 ml of sodium hydroxide test solution, shake well, add 0.4ml of bromophenol blue indicator solution and 10ml of chloroform, with Sodium tetraphenylborate titration solution (0.02mol/L) titration, near the end point must be strong shaking, chloroform layer of blue disappeared, that is. Each 1 ml of Sodium tetraphenylborate titration solution (0.02mol/L) corresponds to 7.969mg of C22H40BrN.
Disinfection antiseptic.
light shielding, sealed storage.
This product is an aqueous solution of benzalkonium bromide, and the hydrocarbon-containing ammonium salt is calculated as C22H40BrN and should be 4.75% ~ 5.25%.
This product is colorless to light yellow clear liquid; Gas fragrance; Strong shaking occurs a lot of foam. Turbidity or precipitation may occur at low temperatures.
6mL of this product was taken and dried by evaporation on a water bath. The residue showed the same reaction according to the identification test of benzalkonium bromide.
precision take 5ml of this product, according to the content of benzalkonium bromide determination method under the item, that is obtained.
with benzalkonium bromide.
5%
light shielding, closed storage.