72299-62-8 - Names and Identifiers
Name | Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-
|
Synonyms | 7-Iodo-1,2,3,4-tetrahydroisoquinoline 1,2,3,4-Tetrahydro-7-iodo-isoquinoline Isoquinoline,1,2,3,4-tetrahydro-7-iodo- Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-
|
CAS | 72299-62-8
|
72299-62-8 - Physico-chemical Properties
Molecular Formula | C9H10IN
|
Molar Mass | 259.09 |
72299-62-8 - Introduction
Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-is an organic compound whose chemical formula is C9H10IN. The following is a description of the nature, use, preparation and safety information of Isoquinoline, 1,2,3,4-tetrahydro-7-iodo:
Nature:
-Appearance: Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-usually a colorless to yellow solid.
-Melting point: Its melting point is about 70-72°C.
-Solubility: Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-can be dissolved in some common organic solvents, such as alcohols, ethers and esters.
Use:
- Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-can be used as a ligand for metal catalysts and participate in chemical reactions in organic synthesis, such as hydrogenation, amination and pyrrolidation reactions.
-It can also be used as an intermediate in organic synthesis for the synthesis of drugs and other organic compounds.
Preparation Method:
Isoquinoline, the preparation of 1,2,3,4-tetrahydro-7-iodo-can be carried out by the following steps:
1. First, 4-methylbenzaldehyde is reacted with hydrochloric acid under appropriate conditions to obtain 4-methylbenzyl alcohol.
2. The 4-methylbenzyl alcohol is continuously reacted with two oxidizing agents, first using a silane-protected alcohol reagent for oxidation, and then using nitric acid for further oxidation to obtain N-methylpyrimidine.
3. Under suitable conditions, N-methyl pyrimidine is reacted with hydroiodic acid to obtain Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-.
Safety Information:
-The toxicity and safety of Isoquinoline, 1,2,3,4-tetrahydro-7-iodo-have not been reported in detail, so appropriate laboratory safety measures should be observed when handling and handling this compound.
-Because it is a potentially harmful compound that may cause harm to human health, direct contact with skin, eyes and mucous membranes should be avoided.
-Experiments need to be performed in a well-ventilated area and using protective gloves, safety glasses and laboratory coats.
-Standard procedures for safety and environmental protection should be followed when handling and disposing of waste.
Last Update:2024-04-09 21:04:16