70894-73-4 - Names and Identifiers
70894-73-4 - Physico-chemical Properties
Molecular Formula | C10H12BrN
|
Molar Mass | 226.11 |
Density | 1.42g/cm3 |
Boling Point | 292.2°C at 760 mmHg |
Flash Point | 130.5°C |
Vapor Presure | 0.00186mmHg at 25°C |
Refractive Index | 1.605 |
70894-73-4 - Introduction
N-(4-bromobenzyl)cyclopropanamine(N-(4-bromobenzyl)cyclopropanamine) is an organic compound with the formula C10H12BrN. The following are some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow liquid
-Density: about 1.38g/cm³
-Melting point: about -12 ℃
-Boiling point: about 268 ℃
-solubility: easily dissolved in ethanol, ether and other common organic solvents.
Use:
N-(4-bromobenzyl)cyclopropanamine is an important organic synthesis intermediate, commonly used in the synthesis of drugs and pesticides and other compounds. It can also be used as a reagent in organic synthesis reactions, such as amination reactions, condensation reactions, etc.
Preparation Method:
The preparation of N-(4-bromobenzyl)cyclopropanamine is usually carried out by the following steps:
1. Benzylamine is reacted with carbon tetrachloride to obtain benzyl tert-butylamine (N-Benzyl-N-tert-butylamine).
2. Carbon tetrabromide was slowly added to benzyl tert-butylamine in an ice-water bath to obtain N-(4-bromobenzyl)-N-tert-butylamine.
3. Finally, a suitable reducing agent, such as metallic zinc, is added to ether or alcohol to react to give N-(4-bromobenzyl)cyclopropanamine.
Safety Information:
N-(4-bromobenzyl)cyclopropanamine is dangerous and irritating. In the process of operation should pay attention to the following safety matters:
-Contact with this compound may cause eye and skin irritation, and care should be taken to avoid direct contact.
-May have effects on the central nervous system, so appropriate protective measures such as gloves, goggles and masks should be worn during operation.
-During use and storage, it should be kept away from flammable substances such as high temperatures, open flames and oxidants.
-When using this compound, it should be operated in a well-ventilated place to avoid inhaling its vapor.
Last Update:2024-04-09 21:00:56