7,7-Difluoronorcarane-3-carboxylic acid

7,7-Difluoronorcarane-3-carboxylic acid - Names and Identifiers

Name	7,7-difluorobicyclo[4.1.0]heptane-3-carboxylic acid
Synonyms	7,7-Difluoronorcarane-3-carboxylic acid 7,7-difluorobicyclo[4.1.0]heptane-3-carboxylic acid Bicyclo[4.1.0]heptane-3-carboxylic acid, 7,7-difluoro-
CAS	1909327-73-6

7,7-Difluoronorcarane-3-carboxylic acid - Physico-chemical Properties

Molecular Formula	C8H10F2O2
Molar Mass	176.16
Density	1.34±0.1 g/cm3(Predicted)
Boling Point	264.7±30.0 °C(Predicted)
pKa	4.26±0.40(Predicted)

7,7-Difluoronorcarane-3-carboxylic acid - Introduction

7,7-difluorobicyclo[4.1.0]heptane-3-carboxylic acid is an organic compound with the chemical formula C8H10F2O2, which is a white solid. It has the following properties:

1. Solubility: 7,7-difluorobicyclo[4.1.0]heptane-3-carboxylic acid is insoluble in water and has good solubility in organic solvents.
2. Chemical properties: under acidic conditions, it can be decarboxylated to generate the corresponding acid.

The main use of this compound is as an intermediate in organic synthesis. It can participate in a series of important organic reactions, such as Catalyst formation, hydrogen transfer, aromatization, decarboxylation and so on. It also has certain applications in drug development and pesticide manufacturing.

7,7-difluorobicyclo[4.1.0]heptane-3-carboxylic acid can be obtained by the following preparation method:
p-difluorobenzoic anhydride (C8H5F2O2) reacts with carbon tetrachloride (CCl4) under the catalysis of aluminum chloride (AlCl3) to generate 7,7-difluorobicyclo[4.1.0]heptane-3-carboxylic acid.

Regarding safety information, due to the lack of specific research, the safety and toxicity data for 7,7-difluorobicyclo[4.1.0]heptane-3-carboxylic acid are insufficient. However, as an organic compound, it may cause irritation and harm to the human body. During use and handling, appropriate safety measures should be taken, such as wearing gloves, goggles and protective clothing, and ensure that the operation is carried out under well-ventilated conditions. If inhaled or exposed to compounds, should promptly seek medical attention.

Last Update：2024-04-09 20:45:29