69677-98-1 - Names and Identifiers
Name | (S)-(+)-1,1'-Bi(2-naphthyl diacetate)
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Synonyms | 2,2'-DIACETOXY-1,1'-BINAPHTHYL DL-1,1'-BI(2-NAPHTHYL DIACETATE) (R)-(-)-1,1'-BI-2-NAPHTHOL DIACETATE (S)-(+)-1,1'-Bi(2-Naphthyl Diacetate) (S)-(+)-1,1'-Bi(2-naphthyl diacetate) (S)-(+)-1,1'-BI(2-NAPHTHYL DIACETATE) 1,1'-binaphthalene-2,2'-diyl diacetate (R)-(-)-2,2'-DIACETOXY-1,1'-BINAPHTHYL (S)-(+)-2,2'-DIACETOXY-1,1'-BINAPHTHYL (S)-[1,1'-Binaphthalene]-2,2'-diyl diacetate
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CAS | 69677-98-1
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InChI | InChI=1/C20H14.2C2H4O2/c1-3-11-17-15(7-1)9-5-13-19(17)20-14-6-10-16-8-2-4-12-18(16)20;2*1-2(3)4/h1-14H;2*1H3,(H,3,4) |
69677-98-1 - Physico-chemical Properties
Molecular Formula | C24H18O4
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Molar Mass | 370.4 |
Density | 1.242±0.06 g/cm3(Predicted) |
Melting Point | 107-111°C(lit.) |
Boling Point | 532.2±45.0 °C(Predicted) |
Specific Rotation(α) | 15 º (c=1.014, THF, 589nm) |
Flash Point | 334.9°C |
Water Solubility | Insoluble |
Vapor Presure | 1.39E-15mmHg at 25°C |
69677-98-1 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 41 - Risk of serious damage to eyes
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
69677-98-1 - Introduction
(S)-( )-1,1 '-Bi(2-naphthyl diacetate), the chemical name is (S)-( )-1,1'-Bi(2-naphthyl diacetate), is a chiral organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid.
-Melting point: about 112-115 ℃.
-Solubility: Soluble in common organic solvents, such as ethanol, chloroform and dimethylformamide, insoluble in water.
Use:
- (S)-( )-1,1 '-Bi (2-napthyl diacetate) is a chiral carrier, which is widely used in enantioselective catalytic reactions.
-It can be used as an asymmetric catalyst for the synthesis of chiral compounds, such as drugs, pesticides and natural products.
-In organic synthesis, it can catalyze ester exchange reactions, nucleophilic substitution reactions and hydroxylation reactions.
Preparation Method:
The synthesis method of
(S)-( )-1,1 '-Bi (2-napthyl diacetate) is more complicated, and the common synthesis routes are as follows:
1. First, 1-naphthol is reduced to 1-binaphthol by hydrogenation.
2. Reaction of 1-binaphthyl alcohol with diacetic anhydride to obtain binaphthol diacetate.
Safety Information:
- (S)-( )-1,1 '-Bi (2-napthyl diacetate) has low toxicity, but it still needs to be used with caution.
-Avoid inhalation, ingestion or skin contact, and take personal protective measures, such as wearing protective gloves and masks.
-Pay attention to a well-ventilated environment during operation to avoid dust or steam.
-In case of accidental contact or ingestion, seek medical attention or consult a professional doctor immediately.
Last Update:2024-04-09 02:00:47