690632-83-8 - Names and Identifiers
690632-83-8 - Physico-chemical Properties
Molecular Formula | C10H8Cl3NS
|
Molar Mass | 280.6 |
Melting Point | 126 °C |
Storage Condition | Sealed in dry,Room Temperature |
690632-83-8 - Introduction
4-(chloromethyl)-2-(3-chlorophenyl)thiazole hydrochloride is an organic compound with the formula C10H7Cl2NS · HCl.
The properties of the compound are as follows:
-Appearance: White crystalline solid
-Solubility: Soluble in water and some organic solvents
-Melting point: about 150-152°C
-Molecular weight: 276.13g/mol
The main uses of the compound are as follows:
-as a pharmaceutical intermediate: can be used for the synthesis of biologically active organic molecules, such as synthetic drugs and pesticides.
-For research: It can be used in different fields of chemical research, such as organic synthesis, drug discovery, pesticides, materials science, etc.
The preparation of the compound can generally be obtained by the following synthetic route:
1. first prepare 2-amino-4-chlorophenylacetic acid (n acid).
2. 2-Amino-4-chlorophenylacetic acid reacts with sodium hypochlorite (NaClO) to generate 4-chloromethyl-2-(3-chlorophenyl)thiazole (4-(chloromethyl)-2-(3-chlorophenyl)thiazole).
3.4-Chloromethyl-2-(3-chlorophenyl)thiazole is reacted with hydrochloric acid (HCl) to generate 4-(chloromethyl)-2-(3-chlorophenyl)thiazole hydrochloride.
Regarding safety information, this compound has not been mentioned in the open literature. However, since it is an organic compound, it should generally follow routine laboratory safety procedures. This includes wearing appropriate protective equipment (such as protective glasses and laboratory gloves), operating in a well-ventilated environment, and avoiding ingestion, inhalation or contact with skin. If the compound needs to be used, it is recommended to operate in an experienced chemical laboratory and strictly follow the relevant safety guidelines.
Last Update:2024-04-09 21:04:16