68622-16-2 - Names and Identifiers
68622-16-2 - Physico-chemical Properties
Molecular Formula | C7H3ClN2O3
|
Molar Mass | 198.56 |
Density | 1.48±0.1 g/cm3(Predicted) |
Melting Point | 94-96°C (dec.)(lit.) |
Boling Point | 286.7±25.0 °C(Predicted) |
Flash Point | 127.2°C |
Vapor Presure | 0.0026mmHg at 25°C |
BRN | 6506805 |
Storage Condition | 2-8℃ |
Sensitive | Moisture Sensitive |
Refractive Index | 1.612 |
MDL | MFCD00037065 |
68622-16-2 - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S22 - Do not breathe dust.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
UN IDs | 2206 |
WGK Germany | 3 |
Hazard Class | 6.1 |
Packing Group | III |
68622-16-2 - Introduction
2-Chloro-5-nitrophenyl isocyanate is an organic compound with the chemical formula C7H3ClN2O3. The following is a description of the nature, use, preparation and safety information of 2-Chloro-5-nitrophenyl isocyanate:
Nature:
-Appearance: 2-Chloro-5-nitrophenyl isocyanate as a yellow to orange crystalline solid.
-Melting point: about 122-124 degrees Celsius.
-Solubility: Soluble in organic solvents such as ethanol, benzene and dimethyl sulfoxide.
Use:
- 2-Chloro-5-nitrophenyl isocyanate is an important organic synthesis intermediate. It can be used to synthesize other compounds, such as drugs, dyes and polymers.
-This compound can also be used as a nitrogenation reagent and isotope labeling reagent in organic synthesis.
Preparation Method:
- 2-Chloro-5-nitrophenyl isocyanate is typically obtained by reacting p-sulfuryl chloride mesylate with 2-chloro-5-nitroaniline. The specific steps include adding thionyl chloride mesylate to the amine solution and reacting at constant temperature to form the target product.
Safety Information:
- 2-Chloro-5-nitrophenyl isocyanate is an organic compound with certain toxicity to human body. Contact with the skin, inhalation or ingestion of the compound may cause health problems.
-During the operation, appropriate protective measures should be taken, such as wearing protective gloves, protective glasses and masks.
-Storage should avoid contact with flammable substances, and keep in a dry, well-ventilated place.
-When handling the compound, follow the relevant safety practices and dispose of the waste properly.
Last Update:2024-04-09 02:00:47