Molecular Formula | C13H13N5O5S2 |
Molar Mass | 383.4 |
Density | 1.89±0.1 g/cm3(Predicted) |
Melting Point | 227° (dec) |
Solubility | Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated, So |
Appearance | Solid |
Color | White to Pale Yellow |
Merck | 14,1951 |
pKa | pKa 2.1 (Uncertain) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Stability | Hygroscopic |
Physical and Chemical Properties | Crystallization, melting point 227 ° C (decomposition). Ceftizoxime Sodium: C13H12N5O5S2Na. [68401-82-1]. White or light gray-yellow crystalline powder, a few odorless. Soluble in water, slightly soluble in methanol, a few insoluble in ethanol, acetone, chloroform, ether or ethyl acetate. Acute toxicity LD50 mice and rats (mg/kg): about 6000, intravenous. |
Use | Mainly used for the treatment of respiratory system, urinary system, bone and joint infections |
RTECS | XI0367375 |
HS Code | 2941906000 |
Toxicity | LD50 intravenous in rat: 8gm/kg |
Reference Show more | 1. Zhao Suhua, fan Hongjie. Serotype identification and drug resistance analysis of avian Escherichia coli in northern Anhui [J]. Journal of Animal Husbandry and Veterinary Medicine, 2017, 49(004):95-98. 2. Dong Jing, Zhang Lushan, Liu Shaochun, Zhang Guodong, Zhou Shun, Yang Qiuhong, AI Xiaohui. Isolation, identification and drug sensitivity analysis of a Klebsiella Pneumonia isolated from Procambarus clarkii [J]. Journal of Huazhong Agricultural University, 2021,40(01):93-98 3. [IF = 3.681] Rao Zhi et al."Determination of Total and Unbound Meropenem, Imipenem/Cilastatin, and Cefoperazone/Sulbactam in Human Plasma: Application for Therapeutic Drug Monitoring in Critically relevant." Ther Drug Monit. 2020 Aug;42(4):578-587 4. [IF = 2.281] Zhiqiang Zhang et al."Contribution of the colicin receptor CirA to biofilm formation, antibotic resistance, and pathogenicity of Salmonella Enteritidis."J Basic Microb. 2020 Jan;60(1):72-81 |