6752-16-5 - Names and Identifiers
Name | 1H-Pyrazolo[3,4-b]pyridin-3-amine
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Synonyms | NSC 48665 OTAVA-BB BB7110952567 3-Aminopyrazolo[3,4-β]pyridine 3-Aminopyrazolo[3,4-b]pyridine 1H-Pyrazolo[3,4-b]pyridin-3-amine 1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE 1H-Pyrazolo[3,4-β]pyridin-3-amine 2H-pyrazolo[3,4-b]pyridin-3-amine 3-Amino-1H-pyrazolo[3,4-β]pyridine 1H-Pyrazolo[3,4-β]pyridin-3-ylamine
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CAS | 6752-16-5
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InChI | InChI=1/C6H6N4/c7-5-4-2-1-3-8-6(4)10-9-5/h1-3H,(H3,7,8,9,10) |
6752-16-5 - Physico-chemical Properties
Molecular Formula | C6H6N4
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Molar Mass | 134.14 |
Density | 1.61±0.1 g/cm3(Predicted) |
Melting Point | 189-192°C |
Boling Point | 315.3±25.0 °C(Predicted) |
Flash Point | 228.7°C |
Solubility | DMSO, Methanol |
Vapor Presure | 8E-07mmHg at 25°C |
Appearance | Solid |
Color | Yellow |
pKa | 7.17±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.806 |
MDL | MFCD04113611 |
6752-16-5 - Risk and Safety
Risk Codes | 25 - Toxic if swallowed
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Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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UN IDs | 2811 |
WGK Germany | 1 |
HS Code | 29331990 |
Hazard Class | IRRITANT |
Packing Group | Ⅲ |
6752-16-5 - Introduction
1H-Pyrazolo[3,4-b]pyridin-3-amine is a polycyclic aromatic compound, and its chemical formula is C8H7N5. The following are some properties, uses, preparation and safety information about the compound:
Nature:
1. Appearance: 1H-Pyrazolo[3,4-b]pyridin-3-amine is colorless crystal, or white to light yellow crystalline powder.
2. Solubility: Soluble in common solvents (such as methanol, ethanol, dimethyl sulfoxide), but low solubility in water.
Use:
1H-Pyrazolo[3,4-b]pyridin-3-amine has important application value in organic synthetic chemistry and pharmaceutical chemistry. It can be used as drug intermediates, catalysts, anti-tumor drugs, etc. It can also be used to study the biological activity and mechanism of action of pyrazolo [3,4-b] pyridine compounds in the field of biology.
Preparation Method:
1H-Pyrazolo[3,4-b]pyridin-3-amine can be prepared by a variety of synthetic methods, such:
1. through the ring reaction: the appropriate pyrazole and amino compounds in the appropriate reaction conditions for the ring reaction can be obtained by the target product.
2. Through the condensation reaction of N-aryl urea: connecting an aryl urea group to the amino group on the pyrazole ring, and then performing a cyclization reaction to obtain the target product.
Safety Information:
1.1 H-Pyrazolo[3,4-b]pyridin-3-amine is a chemical that requires compliance with relevant safety practices and appropriate personal protective equipment.
2. The compound may be irritating to the eyes and skin. When in contact, rinse immediately with plenty of water and seek medical help.
3. Operate under airtight ventilation conditions to avoid inhaling dust or solution vapor.
4. storage should avoid direct sunlight and high temperature, keep in a dry, ventilated place, away from flammable materials and oxidants.
5. Waste shall be disposed in accordance with relevant laws and regulations.
Last Update:2024-04-09 15:17:59