67242-59-5 - Names and Identifiers
67242-59-5 - Physico-chemical Properties
Molecular Formula | C7H8N2O
|
Molar Mass | 136.15 |
Density | 1.137g/mLat 25°C(lit.) |
Boling Point | 71-72°C0.05mm Hg(lit.) |
Flash Point | 229°F |
Vapor Presure | 0.0009mmHg at 25°C |
Appearance | clear liquid |
Color | Colorless to Light orange to Yellow |
BRN | 471767 |
pKa | 4.28±0.10(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | n20/D 1.566(lit.) |
MDL | MFCD00006260 |
67242-59-5 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
HS Code | 29333990 |
67242-59-5 - Introduction
N-formyl-N-methylaminopyridine, also known as N-formyl-N-methylaminopyridine, is an organic compound. Its molecular formula is C9H10N2O and its structure contains a methyl group, a formyl group, and a pyridyl group.
The main properties of the N-formyl-N-methylaminopyridine are as follows:
-Appearance: White to yellow crystal
-Melting point: about 92-95 degrees Celsius
-Solubility: Soluble in most organic solvents, such as alcohols, ethers and esters, insoluble in water.
-Stability: Stable at room temperature, decomposition may occur under light and oxidation conditions.
The main use of N-formyl-N-methylaminopyridine is as a reagent for organic synthesis. It is commonly used as an amination reagent, a protonating agent for electrophilic substrates, an acylation reagent, and a carboxylation reagent. In organic synthesis reactions, N-formyl-N-methylaminopyridine can provide a formyl group (CHO) and a nucleophilic benzylamine (C5H5NCH3).
The preparation methods of N-formyl-N-methylaminopyridine mainly include basic cyclization reaction and acylation reaction of picolinate. The basic cyclization reaction is prepared by reacting pyridine (C5H5NH) with formaldehyde (HCHO) under basic conditions. Acylation of a picolinate is accomplished by reacting a picolinate with formic anhydride (an anhydridizing agent) to form a N-formyl-N-methylaminopyridine.
For safety information, N-formyl-N-methylaminopyridine should be stored in a dry, well-ventilated place, away from ignition and oxidizing agents. In case of contact with skin, eyes or inhalation, rinse immediately with water and seek medical attention. In addition, proper laboratory practices should be observed and protective gloves and eye protection should be worn. If necessary, refer to the relevant safety management information or consult a chemical professional.
Last Update:2024-04-10 22:29:15