67058-76-8 - Names and Identifiers
67058-76-8 - Physico-chemical Properties
Molecular Formula | C7H5BrN2
|
Molar Mass | 197.03 |
Density | 1.770±0.06 g/cm3(Predicted) |
Melting Point | 205-206 °C(Solv: benzene (71-43-2)) |
Boling Point | 357.0±22.0 °C(Predicted) |
Flash Point | 169.702°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 12.99±0.40(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.728 |
67058-76-8 - Introduction
3-bromo-1H-pyrrolo[2,3-c]pyridine(3-bromo-1H-pyrrolo[2,3-c]pyridine) is an organic compound with the formula C8H5BrN2 and a molecular weight of 201.04g/mol.
Its properties are as follows:
Appearance: Colorless to light yellow solid
Melting point: about 90°C
Boiling point: about 355°C
Solubility: Soluble in some organic solvents, such as chloroform, dimethyl sulfinamide, slightly soluble in water.
3-bromo-1H-zirrolo [2,3-c]pyridine have a variety of applications and uses in chemical and pharmaceutical research. Some of the main uses include:
1. as a drug intermediate: can be used to prepare a variety of biologically active compounds, such as drugs, pesticides and photosensitizers.
2. as an organic synthesis reagent: it can be used for the construction of carbon-carbon bond and carbon-heteroatom bond in organic synthesis reaction, such as Suzuki coupling reaction, C- H functionalization reaction, etc.
3. for electronic materials research: with excellent electronic structure and performance, can be used for the preparation of organic optoelectronic devices.
3-bromo-1H-cryolo [2,3-c]pyridine can be prepared by the following methods:
1. N-bromopropanamide reacts with 2-cyanopyridine to obtain N-bromopyrrole [2,3-C] pyridine inhibitor, which is then treated with copper iodide and cuprous salt to obtain the target product.
2. 2-cyanopyridine and sulfoxide first react to obtain N-cyanopyrrole [2,3-C] pyridine, and then undergo bromination reaction to generate the target product.
However, it should be noted that 3-bromo-1H-pyrrolo[2,3-c]pyridine should be handled and stored with caution, and appropriate safety measures need to be taken. Here are some common security messages:
1. the skin and eyes have a stimulating effect, should avoid contact with the skin and eyes, use should wear chemical protective gloves and goggles.
2. may be toxic to aquatic organisms, to avoid pollution to the environment.
3. storage should avoid contact with oxidants, strong acid and alkali and other substances, stored in a cool, dry place.
4. operation should pay attention to good ventilation conditions, avoid inhalation of its vapor or dust.
5. in the process of use, storage and handling, please follow the chemical safety operation procedures to avoid danger.
Last Update:2024-04-09 19:05:51