6698-13-1 - Names and Identifiers
Name | 4-bromo-1,3-benzodioxole
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Synonyms | 4-bromo-1,3-benzodioxole 4-BROMO-1,3-BENZODIOXOLE 1,3-Benzodioxole,4-broMo- 4-Bromo-Benzo[1,3]Dioxole 4-broMobenzo[d][1,3]dioxole 4-broMo-2H-1,3-benzodioxole 4-bromobenzo[d][1,3]dioxole 1-Bromo-2,3-(methylenedioxy)benzene 3-Bromo-1,2-(methylenedioxy)benzene
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CAS | 6698-13-1
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InChI | InChI=1/C7H5BrO2/c8-5-2-1-3-6-7(5)10-4-9-6/h1-3H,4H2 |
6698-13-1 - Physico-chemical Properties
Molecular Formula | C7H5BrO2
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Molar Mass | 201.02 |
Density | 1.721±0.06 g/cm3(Predicted) |
Boling Point | 82 °C |
Flash Point | 109.652°C |
Vapor Presure | 0.066mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.603 |
6698-13-1 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
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Hazard Note | Irritant |
6698-13-1 - Introduction
4-bromo-1,3-benzodioxole(4-bromo-1,3-benzodioxole) is a bromobisoxazole-containing compound. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: 4-bromo-1,3-benzodioxole is a colorless to light yellow solid.
-Melting point: about 69-71 ℃.
-Boiling Point: No public reports.
-Solubility: Soluble in a variety of organic solvents, such as ethanol, dichloromethane, etc.
Use:
- 4-bromo-1,3-benzodioxole is widely used in the field of chemistry, commonly used in the synthesis of organic compounds, drugs and pesticides.
-It can be used as chemical reagents and intermediates for drug synthesis, such as for the synthesis of benzobisoxazole anticancer drugs, anti-anxiety drugs, antidepressant drugs, etc.
Preparation Method:
- 4-bromo-1,3-benzodioxole can be obtained by a variety of synthetic methods, such:
1. brominating m-hydroxybenzoic acid to generate m-hydroxybenzoic acid bromide;
2.4-bromo-1,3-benzodioxole was obtained by reacting m-hydroxybenzoic acid bromide with copper powder and nitrogen in an ether solvent.
Safety Information:
- 4-bromo-1,3-benzodioxole's specific toxicological data and hazard assessment have not been publicly reported. Please ensure adequate safety protection and laboratory operation specifications before use, and evaluate its safety according to specific conditions.
-During use, please follow the relevant safety procedures, such as wearing appropriate protective gloves and glasses, ensuring that the experimental environment is well ventilated, and avoiding inhalation or skin contact.
-Avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
In addition, when using and handling 4-bromo-1,3-benzodioxole, it is recommended to refer to the relevant chemical safety data sheet and material safety data sheet (MSDS).
Last Update:2024-04-09 15:17:59